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IN THIS ISSUE:

Know About Celiac Disease

Posted May 17, 2013

The Academy of Nutrition and Dietetics (formerly the American Diatetic Association) issued the following news release:

Celiac disease is estimated to affect one out of 141 of Americans, or just under 1 percent of the population. The Academy of Nutrition and Dietetics encourages Americans to learn about celiac disease – it can affect your health or someone you love.

What is celiac disease? It is a hereditary, autoimmune disease caused by intolerance to the food protein, gluten – which is found in wheat, barley and rye. When people with celiac disease eat gluten-containing foods, the lining of the small intestine is damaged and eventually destroyed, preventing nutrients from being absorbed adequately. Untreated, celiac disease can lead to nutritional deficiencies, including anemia and osteoporosis, as well as other conditions, including other autoimmune diseases, intestinal cancers, infertility, delayed growth in children and failure to thrive in infants.

“While the only treatment for celiac disease is a gluten-free diet, the good news is, once the diet is started, the road to recover begins, and people with celiac disease can lead long, healthy lives,” says registered dietitian nutritionist and Academy spokesperson Rachel Begun. “Managing celiac disease is not just about eliminating gluten from your diet. It also entails ensuring you get all the vitamins and nutrients your body needs, such as iron, calcium, fiber and B-vitamins like thiamin, riboflavin, niacin and folate.”

An accurate diagnosis for celiac disease is a vital part of restoring health. Symptoms of celiac disease include bloating, gas or abdominal pain, chronic diarrhea or constipation, fatigue, itchy skin rash, tingling in hands and feet, delayed growth or fractured or thin bones. Some people are asymptomatic, meaning they do not experience any of these symptoms. If you or a loved one experience any of these conditions, it may be an indication of celiac disease.

“Do not diagnose yourself. If you have any symptoms, talk with your health care provider and get tested,” Begun says. “It’s important to keep eating a normal gluten-containing diet while being tested to ensure an accurate diagnosis. If you are diagnosed with celiac disease, a registered dietitian nutritionist will help you understand which foods are safe to eat and ensure you are getting the important nutrients your body needs.”

Many healthy foods are naturally gluten-free, such as fruits, vegetables, lean meats, poultry, fish, eggs, beans, legumes, soy, nuts, as well as the grains amaranth, buckwheat, corn, rice, teff and quinoa. Plus, there are a number of gluten-free flours made from almond meal, chickpeas and garbanzo beans, brown rice, coconut, potato, sorghum, tapioca and white rice.

For more information on celiac disease take a look at the Academy’s Celiac Disease resources, as well as the up-to-date, handy Gluten Detective App (https://www.eatright.org/shop/product.aspx?id=6442470637), which can simplify gluten-free grocery shopping, as well tips and tools to access on your smartphone.

Visit the Academy of Nutrition and Dietetics at www.eatright.org to locate a registered dietitian in your area.

TNS mv45 130511-4341443 61MarlynVitin

© 2013 Targeted News Service

The Academy of Nutrition and Dietetics (formerly the American Diatetic Association) issued the following news release:

Celiac disease is estimated to affect one out of 141 of Americans, or just under 1 percent of the population. The Academy of Nutrition and Dietetics encourages Americans to learn about celiac disease - it can affect your health or someone you love.

What is celiac disease? It is a hereditary, autoimmune disease caused by intolerance to the food protein, gluten - which is found in wheat, barley and rye. When people with celiac disease eat gluten-containing foods, the lining of the small intestine is damaged and eventually destroyed, preventing nutrients from being absorbed adequately. Untreated, celiac disease can lead to nutritional deficiencies, including anemia and osteoporosis, as well as other conditions, including other autoimmune diseases, intestinal cancers, infertility, delayed growth in children and failure to thrive in infants.

"While the only treatment for celiac disease is a gluten-free diet, the good news is, once the diet is started, the road to recover begins, and people with celiac disease can lead long, healthy lives," says registered dietitian nutritionist and Academy spokesperson Rachel Begun. "Managing celiac disease is not just about eliminating gluten from your diet. It also entails ensuring you get all the vitamins and nutrients your body needs, such as iron, calcium, fiber and B-vitamins like thiamin, riboflavin, niacin and folate."

An accurate diagnosis for celiac disease is a vital part of restoring health. Symptoms of celiac disease include bloating, gas or abdominal pain, chronic diarrhea or constipation, fatigue, itchy skin rash, tingling in hands and feet, delayed growth or fractured or thin bones. Some people are asymptomatic, meaning they do not experience any of these symptoms. If you or a loved one experience any of these conditions, it may be an indication of celiac disease.

"Do not diagnose yourself. If you have any symptoms, talk with your health care provider and get tested," Begun says. "It's important to keep eating a normal gluten-containing diet while being tested to ensure an accurate diagnosis. If you are diagnosed with celiac disease, a registered dietitian nutritionist will help you understand which foods are safe to eat and ensure you are getting the important nutrients your body needs."

Many healthy foods are naturally gluten-free, such as fruits, vegetables, lean meats, poultry, fish, eggs, beans, legumes, soy, nuts, as well as the grains amaranth, buckwheat, corn, rice, teff and quinoa. Plus, there are a number of gluten-free flours made from almond meal, chickpeas and garbanzo beans, brown rice, coconut, potato, sorghum, tapioca and white rice.

For more information on celiac disease take a look at the Academy's Celiac Disease resources, as well as the up-to-date, handy Gluten Detective App (https://www.eatright.org/shop/product.aspx?id=6442470637), which can simplify gluten-free grocery shopping, as well tips and tools to access on your smartphone.

Visit the Academy of Nutrition and Dietetics at www.eatright.org to locate a registered dietitian in your area.

TNS mv45 130511-4341443 61MarlynVitin

© 2013 Targeted News Service

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Diabetes Drugs Can Deplete Certain Nutrients

Posted March 3, 2013

Dear Pharmacist, I have your “Diabetes Without Drugs” book and it has helped me, but I’m still on two of the original 5 medications for this condition. What nutrients should I take with my medicine? — B.B., Micanopy, Fla.

For my new readers, the term “drug mugger” refers to how medication (or foods) reduce levels of vitamins, minerals and beneficial flora (probiotics) and cause side effects.

Metformin, which belongs to the biguanide class, depletes probiotics, vitamin B12 and folic acid. This deficiency may cause homocysteine to rise. You can measure homocysteine in the blood.

Up to 30 percent of people taking biguanide drugs (like metformin) experience poor absorption of vitamin B12, according to Diabetologia (1983) and withdrawal of this drug resulted in normal absorption in only half of those with malabsorption.

In other words, just taking the medicine means that half of you still need long-term B12 supplementation, because your B12 won’t automatically rise upon discontinuation of the drug.

Low B12 and folate could contribute or possibly cause tingling or numbness in the hands or feet (termed neuropathy), depression, megaloblastic anemia, weakness, rapid heart rate, confusion, memory loss, dementia, diarrhea/constipation, chronic fatigue, sciatica, as well as a higher risk of heart disease.

Do you think I’m telling you to stop your medicine? I’m not.

I am trying to keep you safe and help you learn what nutrients to put back. Replenishing what the drug mugger stole reduces your risk of side effects and remains compliant with your medication.

Hopefully your doctor has my book and has already told you to take a good B12 and folic acid supplement, as well as (and this is important) a good probiotic, because you require beneficial bacteria to manufacture B12.

Sulfonylureas (glipizide, glyburide, glimepiride) can increase the risk of CoQ10 deficiency according to a study in the Journal of Medicine. That can lead to fatigue, shortness of breath and heart arrhythmias.

info@dearpharmacist.com

Dear Pharmacist, I have your "Diabetes Without Drugs" book and it has helped me, but I'm still on two of the original 5 medications for this condition. What nutrients should I take with my medicine? -- B.B., Micanopy, Fla.

For my new readers, the term "drug mugger" refers to how medication (or foods) reduce levels of vitamins, minerals and beneficial flora (probiotics) and cause side effects.

Metformin, which belongs to the biguanide class, depletes probiotics, vitamin B12 and folic acid. This deficiency may cause homocysteine to rise. You can measure homocysteine in the blood.

Up to 30 percent of people taking biguanide drugs (like metformin) experience poor absorption of vitamin B12, according to Diabetologia (1983) and withdrawal of this drug resulted in normal absorption in only half of those with malabsorption.

In other words, just taking the medicine means that half of you still need long-term B12 supplementation, because your B12 won't automatically rise upon discontinuation of the drug.

Low B12 and folate could contribute or possibly cause tingling or numbness in the hands or feet (termed neuropathy), depression, megaloblastic anemia, weakness, rapid heart rate, confusion, memory loss, dementia, diarrhea/constipation, chronic fatigue, sciatica, as well as a higher risk of heart disease.

Do you think I'm telling you to stop your medicine? I'm not.

I am trying to keep you safe and help you learn what nutrients to put back. Replenishing what the drug mugger stole reduces your risk of side effects and remains compliant with your medication.

Hopefully your doctor has my book and has already told you to take a good B12 and folic acid supplement, as well as (and this is important) a good probiotic, because you require beneficial bacteria to manufacture B12.

Sulfonylureas (glipizide, glyburide, glimepiride) can increase the risk of CoQ10 deficiency according to a study in the Journal of Medicine. That can lead to fatigue, shortness of breath and heart arrhythmias.

info@dearpharmacist.com

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More Magnesium May Make Sense

Posted October 13, 2012

Dear Pharmacist, Dr. Oz said magnesium was the No. 1 thing for exhaustion. Do you agree? What are the best supplements? – C.T., Charlotte, N.C.

Magnesium is definitely needed for energy production. But no, I don’t agree it’s the “No. 1″ thing you need. Symptoms of mag deficiency include sugar and chocolate cravings, cardiac arrhythmias, irritability, panic attacks, anxiety, muscle weakness or spasms, tearfulness, depression, personality changes, constipation, leg cramps, and fatigue.

Your body needs mag all day long; some of it is used to fuel biochemical reactions, you urinate some out and require some to make dopamine (a happy brain chemical). Here’s what Dr. Oz didn’t say on that segment: Magnesium is leached by medications, something I’ve termed the “drug mugging” effect. More than 200 medications deplete mag, among them antacids, antibiotics, digoxin, heartburn/reflux medications, birth control, methylphenidate, corticosteroids, almost all blood pressure medications and diuretics.

There are other muggers too, including coffee, black and green tea, green coffee bean extract, and white refined sugar. Just having Celiac disease, Crohn’s, inflammatory bowel disease and chronic diarrhea can reduce magnesium.

Eating nutrient-dense foods is always my first choice to restore minerals, but in this case, eating magnesium-rich foods may not be enough to correct a serious deficiency. The best supplements are “chelated magnesium” or “magnesium glycinate” or my favorite “magnesium taurate.” That last one provides your body with both magnesium and taurine, and taurine is imperative for your heart cells!

My point is that fatigue is not usually due to low mag. There’s more involved, such as iron deficiency anemia, or poor B vitamin status. My column “Stressed Out?” can truly help you, so I’ve archived it at my site tulsaworld.com/Pharmacist

info@dearpharmacist.com

Dear Pharmacist, Dr. Oz said magnesium was the No. 1 thing for exhaustion. Do you agree? What are the best supplements? - C.T., Charlotte, N.C.

Magnesium is definitely needed for energy production. But no, I don't agree it's the "No. 1" thing you need. Symptoms of mag deficiency include sugar and chocolate cravings, cardiac arrhythmias, irritability, panic attacks, anxiety, muscle weakness or spasms, tearfulness, depression, personality changes, constipation, leg cramps, and fatigue.

Your body needs mag all day long; some of it is used to fuel biochemical reactions, you urinate some out and require some to make dopamine (a happy brain chemical). Here's what Dr. Oz didn't say on that segment: Magnesium is leached by medications, something I've termed the "drug mugging" effect. More than 200 medications deplete mag, among them antacids, antibiotics, digoxin, heartburn/reflux medications, birth control, methylphenidate, corticosteroids, almost all blood pressure medications and diuretics.

There are other muggers too, including coffee, black and green tea, green coffee bean extract, and white refined sugar. Just having Celiac disease, Crohn's, inflammatory bowel disease and chronic diarrhea can reduce magnesium.

Eating nutrient-dense foods is always my first choice to restore minerals, but in this case, eating magnesium-rich foods may not be enough to correct a serious deficiency. The best supplements are "chelated magnesium" or "magnesium glycinate" or my favorite "magnesium taurate." That last one provides your body with both magnesium and taurine, and taurine is imperative for your heart cells!

My point is that fatigue is not usually due to low mag. There's more involved, such as iron deficiency anemia, or poor B vitamin status. My column "Stressed Out?" can truly help you, so I've archived it at my site tulsaworld.com/Pharmacist

info@dearpharmacist.com

Tags: , , , , , , , , , , , , , , , , , , ,



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Pros and Cons of Going Totally Vegan

Posted May 26, 2012

Several high-profile public figures have made headlines recently about their decision to go vegan, spurring increased interest and debate about this plant-based diet plan.

Among them are Ellen DeGeneres, the Emmy award-winning comedian and her wife, actress Portia de Rossi, who have purged their diets of all animal products, including milk and eggs.

Former U.S. President Bill Clinton recently spoke with DeGeneres on her talk-variety show about his decision to adopt a vegan diet, too. Other famous vegans include: Carrie Underwood, Ted Danson, Mike Tyson, Alec Baldwin, Alicia Silverstone and Lea Michele.

Vegetarian vs. Vegan

According to a 2011 poll by The Vegetarian Resource Group, approximately 5 percent of adults in the U.S. say they are vegetarian, which means they never eat meat, fish, seafood or poultry.

About half of those vegetarians also are vegan, which means they also do not consume any animal products or by-products, according to the VRG.

In addition to staying away from flesh foods, dairy and eggs, vegans avoid fur, leather, wool, down and cosmetics or chemical products tested on animals for a variety of reasons, including those related to animal rights, the environment and health, according to Vegan Action, a nonprofit organization dedicated to educating the public about the benefits of a vegan lifestyle.

With the vegan lifestyle getting increased attention, we spoke to nine local experts and asked them to explain the pros and cons of this diet and lifestyle choice and how to make the change safely.

Benefits of vegan diet

Local dietitians said when done right, going vegan comes with numerous health perks.

Less fat, more fruits and veggies: Ellen Thompson, a registered, licensed dietitian in Ohio who is based out of Springfield and works throughout the Miami Valley, said vegans are removing saturated fats from their diet and are likely to eat more fruits and vegetables.

Decreased health risks: The vitamins and minerals in fruits and vegetables may lead to a decreased risk for certain types of cancer, said Carla Metzler, a registered, licensed dietitian who works at Fort Hamilton Hospital.

A vegan diet may prevent or reduce the risk of heart disease, diabetes and obesity, according to both Joan Wire, a registered, licensed dietitian in Ohio who runs a counseling business called Real Well and who works out of LaDeSpa in Oakwood, and Kathryn Hines, a registered, licensed dietitian in Ohio who works at Springfield Regional Medical Center.

Going vegan also may reduce the risk of high blood pressure, constipation, breast cancer, colon cancer, diverticular disease, gallstones, irritable bowel syndrome and appendicitis, said Mara Lamb, a registered, licensed dietitian who owns her own practice called Nutrition Therapy Clinic in Dayton.

Lower BMI: Vegans tend to have a lower body mass index and a lower amount of LDL cholesterol in their bodies, which clogs arteries, said Carol Nartker, a diabetes nutrition educator and a registered, licensed dietitian in Ohio who works at the Diabetes Wellness Center of Atrium Medical Center in Middletown.

In fact, “Forks over Knives,” a 2011 documentary, has recently drawn attention for examining the claim that most, and perhaps all, degenerative diseases can be controlled or eliminated by rejecting animal-based and processed foods, said Rich Cohen, a registered dietitian, licensed dietitian in Ohio, who works at Kettering Weight Loss Solutions within the Kettering Health Network.

“Our food supply is not very natural,” Cohen said. ” … The vegan diet seems to be offering perhaps some kind of a nutritional medicine approach, particularly with people with cardiovascular disease.”

Allergy, sinus relief? Wire also said individuals who turn to a vegan diet may realize allergy symptoms and sinus problems are reduced or eliminated once they stop consuming dairy.

Downsides of going vegan

On the other hand, there are potential negative health effects associated with going vegan, dietitians said.

Risk of deficiencies: According to Thompson, if a vegan is not careful, he or she may develop nutritional deficiencies due to a lack of dairy and meat products in their diet.

Some dietitians are concerned that vegans do not receive an adequate amount of amino acids, Vitamin B12, Vitamin D, Calcium, protein and iron, Thompson said.

Dr. Andrew Dyer, an associate clinician at Back to Health Center in Dayton, said protein deficiencies can lead to fatigue, a lack of energy and an inability to complete daily tasks, he said.

Additionally, those participating in exercise and athletics may have a difficult time healing and repairing post workout without getting enough protein in their diet, he said.

A lack of Vitamin B12 in a diet may lead to anemia, Nartker said.

Bone health: In addition, a lack of calcium may put a person at risk for developing a fragile bone structure, according to Metzler.

“Chronic nutritional deficiencies can affect the quality of one’s life, how they feel, how they function from day to day,” Nartker said.

What vegans should, should not eat

Vegans should avoid overly processed foods and choose whole foods, which are closer to “what Mother Nature intended” for people to consume, Wire recommends.

Vegans must minimize their intake of “junk food,” which includes sweets and snacks high in fat, Lamb said.

Acclimating to new tastes typically takes about three weeks, she said.

Importance of planning

Careful planning is key to ensuring a person adopts a long-term, healthy vegan diet, Thompson said. It’s also important that vegans remember that a healthy lifestyle means they get enough exercise and sleep, too, she said.

“It’s not what you do once in a while,” Thompson said. “It’s what you do every day.”

Start by doing research.

“Don’t go in cold turkey,” Wire said. ” … You could miss out on getting the right types of protein.”

Thompson said vegans should speak to a dietitian in order to make sure they are following a healthy diet plan.

New vegans should change their diet slowly, and should see a doctor if they have health issues such as diabetes, she said.

The Associated Press contributed to this story. Contact this reporter at (937) 225-2122 or Jacqueline.Boyle@coxinc.com.

©2012 the Dayton Daily News (Dayton, Ohio)

Visit the Dayton Daily News (Dayton, Ohio) at www.daytondailynews.com

Several high-profile public figures have made headlines recently about their decision to go vegan, spurring increased interest and debate about this plant-based diet plan.

Among them are Ellen DeGeneres, the Emmy award-winning comedian and her wife, actress Portia de Rossi, who have purged their diets of all animal products, including milk and eggs.

Former U.S. President Bill Clinton recently spoke with DeGeneres on her talk-variety show about his decision to adopt a vegan diet, too. Other famous vegans include: Carrie Underwood, Ted Danson, Mike Tyson, Alec Baldwin, Alicia Silverstone and Lea Michele.

Vegetarian vs. Vegan

According to a 2011 poll by The Vegetarian Resource Group, approximately 5 percent of adults in the U.S. say they are vegetarian, which means they never eat meat, fish, seafood or poultry.

About half of those vegetarians also are vegan, which means they also do not consume any animal products or by-products, according to the VRG.

In addition to staying away from flesh foods, dairy and eggs, vegans avoid fur, leather, wool, down and cosmetics or chemical products tested on animals for a variety of reasons, including those related to animal rights, the environment and health, according to Vegan Action, a nonprofit organization dedicated to educating the public about the benefits of a vegan lifestyle.

With the vegan lifestyle getting increased attention, we spoke to nine local experts and asked them to explain the pros and cons of this diet and lifestyle choice and how to make the change safely.

Benefits of vegan diet

Local dietitians said when done right, going vegan comes with numerous health perks.

Less fat, more fruits and veggies: Ellen Thompson, a registered, licensed dietitian in Ohio who is based out of Springfield and works throughout the Miami Valley, said vegans are removing saturated fats from their diet and are likely to eat more fruits and vegetables.

Decreased health risks: The vitamins and minerals in fruits and vegetables may lead to a decreased risk for certain types of cancer, said Carla Metzler, a registered, licensed dietitian who works at Fort Hamilton Hospital.

A vegan diet may prevent or reduce the risk of heart disease, diabetes and obesity, according to both Joan Wire, a registered, licensed dietitian in Ohio who runs a counseling business called Real Well and who works out of LaDeSpa in Oakwood, and Kathryn Hines, a registered, licensed dietitian in Ohio who works at Springfield Regional Medical Center.

Going vegan also may reduce the risk of high blood pressure, constipation, breast cancer, colon cancer, diverticular disease, gallstones, irritable bowel syndrome and appendicitis, said Mara Lamb, a registered, licensed dietitian who owns her own practice called Nutrition Therapy Clinic in Dayton.

Lower BMI: Vegans tend to have a lower body mass index and a lower amount of LDL cholesterol in their bodies, which clogs arteries, said Carol Nartker, a diabetes nutrition educator and a registered, licensed dietitian in Ohio who works at the Diabetes Wellness Center of Atrium Medical Center in Middletown.

In fact, "Forks over Knives," a 2011 documentary, has recently drawn attention for examining the claim that most, and perhaps all, degenerative diseases can be controlled or eliminated by rejecting animal-based and processed foods, said Rich Cohen, a registered dietitian, licensed dietitian in Ohio, who works at Kettering Weight Loss Solutions within the Kettering Health Network.

"Our food supply is not very natural," Cohen said. " ... The vegan diet seems to be offering perhaps some kind of a nutritional medicine approach, particularly with people with cardiovascular disease."

Allergy, sinus relief? Wire also said individuals who turn to a vegan diet may realize allergy symptoms and sinus problems are reduced or eliminated once they stop consuming dairy.

Downsides of going vegan

On the other hand, there are potential negative health effects associated with going vegan, dietitians said.

Risk of deficiencies: According to Thompson, if a vegan is not careful, he or she may develop nutritional deficiencies due to a lack of dairy and meat products in their diet.

Some dietitians are concerned that vegans do not receive an adequate amount of amino acids, Vitamin B12, Vitamin D, Calcium, protein and iron, Thompson said.

Dr. Andrew Dyer, an associate clinician at Back to Health Center in Dayton, said protein deficiencies can lead to fatigue, a lack of energy and an inability to complete daily tasks, he said.

Additionally, those participating in exercise and athletics may have a difficult time healing and repairing post workout without getting enough protein in their diet, he said.

A lack of Vitamin B12 in a diet may lead to anemia, Nartker said.

Bone health: In addition, a lack of calcium may put a person at risk for developing a fragile bone structure, according to Metzler.

"Chronic nutritional deficiencies can affect the quality of one's life, how they feel, how they function from day to day," Nartker said.

What vegans should, should not eat

Vegans should avoid overly processed foods and choose whole foods, which are closer to "what Mother Nature intended" for people to consume, Wire recommends.

Vegans must minimize their intake of "junk food," which includes sweets and snacks high in fat, Lamb said.

Acclimating to new tastes typically takes about three weeks, she said.

Importance of planning

Careful planning is key to ensuring a person adopts a long-term, healthy vegan diet, Thompson said. It's also important that vegans remember that a healthy lifestyle means they get enough exercise and sleep, too, she said.

"It's not what you do once in a while," Thompson said. "It's what you do every day."

Start by doing research.

"Don't go in cold turkey," Wire said. " ... You could miss out on getting the right types of protein."

Thompson said vegans should speak to a dietitian in order to make sure they are following a healthy diet plan.

New vegans should change their diet slowly, and should see a doctor if they have health issues such as diabetes, she said.

The Associated Press contributed to this story. Contact this reporter at (937) 225-2122 or Jacqueline.Boyle@coxinc.com.

©2012 the Dayton Daily News (Dayton, Ohio)

Visit the Dayton Daily News (Dayton, Ohio) at www.daytondailynews.com

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Women More Likely to Die from Heart Attacks

Posted March 16, 2012

A new study out of Florida finds women are less likely to get immediate treatment for heart attacks and are more likely to die in the hospital than men.

The Lakeland Regional Medical Center in Florida tracked 1.1 million patients. Women had a 15 percent chance of dying of a heart attack in the hospital compared to men’s 10 percent. One of the reasons for the higher numbers among women, 42 percent of women never experienced the classic heart attack symptom of chest pain or pressure.

“Women often present with suddenly feeling tired, fatigue, nausea, reduced exercise tolerance, rather vague,” said Dr. Ed Fry, cardiologist at St. Vincent Heart Center.

Dr. Fry said one of the reasons for the different symptoms is because women have smaller blood vessels than men. It’s something he and his colleagues are studying at St. Vincent’s Heart Center.

Cynthia Haverstick is a heart attack survivor. She said her symptoms weren’t very clear.

“I wouldn’t be able to breathe properly, I would tire easily, I had trouble lifting things. I just figured it was me and it would go away eventually.”

Haverstick said it all hit her what was going on. In May 2010, it was confirmed.

“Once I realized what was going on and I got to the hospital, they confirmed I had a heart attack.”

Dr. Fry said it’s important to talk to your primary care doctor and know your own risks. There are things you can do right now to help. Know your family history, exercise and watch your weight. Know your cholesterol, blood pressure, blood sugar and if you’re pre-diabetic or diabetic. Most importantly, he said you shouldn’t smoke and if you do, quit.

“We know smoking is one of the most serious risk factors and one of the most modifiable risk factors.”

Cynthia admits she is a typical mom and said she’s lucky there was no permanent damage to her heart.

“We think of everyone else and often time put ourselves on the bottom of the list.”

©2012 WXIN-TV (Indianapolis)

Visit WXIN-TV (Indianapolis) at www.fox59.com

A new study out of Florida finds women are less likely to get immediate treatment for heart attacks and are more likely to die in the hospital than men.

The Lakeland Regional Medical Center in Florida tracked 1.1 million patients. Women had a 15 percent chance of dying of a heart attack in the hospital compared to men's 10 percent. One of the reasons for the higher numbers among women, 42 percent of women never experienced the classic heart attack symptom of chest pain or pressure.

"Women often present with suddenly feeling tired, fatigue, nausea, reduced exercise tolerance, rather vague," said Dr. Ed Fry, cardiologist at St. Vincent Heart Center.

Dr. Fry said one of the reasons for the different symptoms is because women have smaller blood vessels than men. It's something he and his colleagues are studying at St. Vincent's Heart Center.

Cynthia Haverstick is a heart attack survivor. She said her symptoms weren't very clear.

"I wouldn't be able to breathe properly, I would tire easily, I had trouble lifting things. I just figured it was me and it would go away eventually."

Haverstick said it all hit her what was going on. In May 2010, it was confirmed.

"Once I realized what was going on and I got to the hospital, they confirmed I had a heart attack."

Dr. Fry said it's important to talk to your primary care doctor and know your own risks. There are things you can do right now to help. Know your family history, exercise and watch your weight. Know your cholesterol, blood pressure, blood sugar and if you're pre-diabetic or diabetic. Most importantly, he said you shouldn't smoke and if you do, quit.

"We know smoking is one of the most serious risk factors and one of the most modifiable risk factors."

Cynthia admits she is a typical mom and said she's lucky there was no permanent damage to her heart.

"We think of everyone else and often time put ourselves on the bottom of the list."

©2012 WXIN-TV (Indianapolis)

Visit WXIN-TV (Indianapolis) at www.fox59.com

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Flutter in Chest May Be AFib

Posted Mar 8, 2012

That fluttering, flopping or racing in your chest could be caused by more than a new romance.

Atrial fibrillation, or AFib, is the most common type of heart rhythm abnormality (arrhythmia). It interferes with your heart’s natural pacemaker, often causing palpitations which feel like a “flutter” of the heart.

This can interfere with the way that the heart pumps blood. It is most common in patients over the age of 65 and in those with thyroid disease, high blood pressure, coronary artery disease and other medical conditions.

Symptoms of AFib can include trouble breathing, sweating, fainting, dizziness, pressure or pain in the chest, and fatigue or weakness.

However, many may have little or no signs at all, so it is important to see a physician if you are experiencing even one of these symptoms.

Once a patient is diagnosed with AFib, there are several options to help control the arrhythmia and prevent stroke, generally first through prescription medications.

If this is ineffective, other procedures available include electrical cardioversion, which can restore regular heartbeat through an electric shock to the heart done under anesthesia.

Electrical cardioversion, however, does not prevent against future arrhythmia. Maintaining a normal rhythm may require anti- arrhythmic drugs.

Catheter ablation uses flexible wires, under X-ray guidance, to deliver bursts of radiofrequency to affected areas of the heart, thereby restoring the heart’s electrical signals.

Symptoms of an arrhythmia or other cardiac concerns should not be ignored. Often times your physician can treat these with both dietary and lifestyle changes, helping you to feel better in time to enjoy your new romance.

That fluttering, flopping or racing in your chest could be caused by more than a new romance.

Atrial fibrillation, or AFib, is the most common type of heart rhythm abnormality (arrhythmia). It interferes with your heart's natural pacemaker, often causing palpitations which feel like a "flutter" of the heart.

This can interfere with the way that the heart pumps blood. It is most common in patients over the age of 65 and in those with thyroid disease, high blood pressure, coronary artery disease and other medical conditions.

Symptoms of AFib can include trouble breathing, sweating, fainting, dizziness, pressure or pain in the chest, and fatigue or weakness.

However, many may have little or no signs at all, so it is important to see a physician if you are experiencing even one of these symptoms.

Once a patient is diagnosed with AFib, there are several options to help control the arrhythmia and prevent stroke, generally first through prescription medications.

If this is ineffective, other procedures available include electrical cardioversion, which can restore regular heartbeat through an electric shock to the heart done under anesthesia.

Electrical cardioversion, however, does not prevent against future arrhythmia. Maintaining a normal rhythm may require anti- arrhythmic drugs.

Catheter ablation uses flexible wires, under X-ray guidance, to deliver bursts of radiofrequency to affected areas of the heart, thereby restoring the heart's electrical signals.

Symptoms of an arrhythmia or other cardiac concerns should not be ignored. Often times your physician can treat these with both dietary and lifestyle changes, helping you to feel better in time to enjoy your new romance.

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Heart Awareness Month

Posted Feb 4, 2012

February is Heart Awareness Month, and Friday marks National Wear Red Day to raise awareness about heart disease, such as how to recognize it, treat it and prevent it.

Heart disease is the No. 1 killer of women, according to the American Heart Association.

Jean Julius, a registered nurse with the Owensboro Medical Health System HealthPark, said a person can improve heart health by not smoking, avoiding secondhand smoke, staying active by walking every day and eating a healthy, balanced diet with less salt.

“You should also check your blood pressure often,” Julius said. “If you’re on blood pressure medicine, then a physician checks you regularly. Other than that, get it checked once a year, but as we age, the blood pressure goes higher.”

Recommended blood pressure is 120 over 80.

According to the AHA, more women now die from coronary disease in the United States each year than do men. One theory is that the disease has progressed further without a woman being aware of it. Women, historically, don’t visit cardiologists as much as men.

“Men have that heavy feeling in their chest, like an elephant is sitting on it,” Julius said. “That’s not always true with women. They feel tired, fatigued and a shortness of breath.

“Women may feel nauseated or an ache in the chest. They think that’s indigestion, which men do also. And just like in men, the pain radiates to the jaw, neck and shoulders. That’s a sign that you should respond right away.”

At that point, a person should call 911 and not go to a clinic.

“As soon as EMT’s arrive, they’ll be in communication with the emergency room,” Julius said. “When you get there, there will be no waiting in the waiting room, you’ll be seen immediately.”

Julius said it’s better to be on the safe side and go to the ER and find out you didn’t have a heart attack than not going when you did have one. Blockages prevent oxygen in the blood from getting where it needs to go.

“The lack of circulation of blood to the heart muscle is what’s causing the pain,” she said.

Women also tend to have higher cholesterol than men. Additionally, high triglycerides tend to more negatively affect women in terms of causing blockages and heart attacks.

Fat in the artery is called plaque, and plaque adheres to an artery wall, building up and slowly eroding into the artery. Women are more prone to erosion, meaning the plaque erodes into the bloodstream, creating the likelihood that it will lodge somewhere to cause a blood clot, and block the blood flow, causing a heart attack.

Rich Suwanski, 691-7315

©2012 the Messenger-Inquirer (Owensboro, Ky.)

Visit the Messenger-Inquirer (Owensboro, Ky.) at www.messenger-inquirer.com

Distributed by MCT Information Services

February is Heart Awareness Month, and Friday marks National Wear Red Day to raise awareness about heart disease, such as how to recognize it, treat it and prevent it.

Heart disease is the No. 1 killer of women, according to the American Heart Association.

Jean Julius, a registered nurse with the Owensboro Medical Health System HealthPark, said a person can improve heart health by not smoking, avoiding secondhand smoke, staying active by walking every day and eating a healthy, balanced diet with less salt.

"You should also check your blood pressure often," Julius said. "If you're on blood pressure medicine, then a physician checks you regularly. Other than that, get it checked once a year, but as we age, the blood pressure goes higher."

Recommended blood pressure is 120 over 80.

According to the AHA, more women now die from coronary disease in the United States each year than do men. One theory is that the disease has progressed further without a woman being aware of it. Women, historically, don't visit cardiologists as much as men.

"Men have that heavy feeling in their chest, like an elephant is sitting on it," Julius said. "That's not always true with women. They feel tired, fatigued and a shortness of breath.

"Women may feel nauseated or an ache in the chest. They think that's indigestion, which men do also. And just like in men, the pain radiates to the jaw, neck and shoulders. That's a sign that you should respond right away."

At that point, a person should call 911 and not go to a clinic.

"As soon as EMT's arrive, they'll be in communication with the emergency room," Julius said. "When you get there, there will be no waiting in the waiting room, you'll be seen immediately."

Julius said it's better to be on the safe side and go to the ER and find out you didn't have a heart attack than not going when you did have one. Blockages prevent oxygen in the blood from getting where it needs to go.

"The lack of circulation of blood to the heart muscle is what's causing the pain," she said.

Women also tend to have higher cholesterol than men. Additionally, high triglycerides tend to more negatively affect women in terms of causing blockages and heart attacks.

Fat in the artery is called plaque, and plaque adheres to an artery wall, building up and slowly eroding into the artery. Women are more prone to erosion, meaning the plaque erodes into the bloodstream, creating the likelihood that it will lodge somewhere to cause a blood clot, and block the blood flow, causing a heart attack.

Rich Suwanski, 691-7315

©2012 the Messenger-Inquirer (Owensboro, Ky.)

Visit the Messenger-Inquirer (Owensboro, Ky.) at www.messenger-inquirer.com



Distributed by MCT Information Services

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Don’t Suffer with SAD This Winter

Posted Dec 26, 2011

-Angela Greenwalt blames Duluth.

“They should give out Prozac at the borders of Duluth,” the Harbor Highlands resident said.

It’s worse in Barnum, Bobbie Mistretta said.

“We live in what they call a moraine,” the retiree said. “We get even less sun than in Duluth.”

Greenwalt and Mistretta are among Northlanders who have begun their annual battle with SAD — Seasonal Affective Disorder. As the days grow shorter, they’re gripped by fatigue and lethargy. They fight back with Vitamin D, exercise, lifestyle changes and specially designed, extremely bright lights.

It’s no illusion, said Tom Lewandowski, a psychotherapist at St. Luke’s hospital and licensed independent social worker with expertise in SAD. The transition to winter acts as a depressant for many people, and it gets worse as you go north.

“In Florida, the incidence of SAD is about 1.4 percent, whereas in New Hampshire — which is about the same latitude as Duluth — it’s around 10 percent,” Lewandowski said. “It keeps increasing as you go north. It pretty much maxes out when

you get to Anchorage and Helsinki (Finland), and it can get as high as 15 percent.”

Winter blues

Those numbers refer specifically to SAD, a clinical illness that accompanies other forms of depression, Lewandowski said. Many more Northlanders experience some degree of depressive symptoms around this time of year.

“You can have the winter blues, which probably affects 30 to 40 percent of the population,” he said. “But usually that is a passing phase, usually at the onset of winter. Then it kind of fades. … In clinical Seasonal Affective Disorder, that ‘Oh no, the season’s changing’ keeps going and gets more intense.”

That’s how it works for Rachel Bartczak.

“In January and February you go to work and it’s dark out and you come home and it’s dark out,” the Cloquet woman said. “You get through New Year’s and there’s nothing to look forward to.”

Bartczak, 30, said she has battled depression since she was in high school.

“When I’m having a really bad day, when I’m feeling slummy, I don’t want to get out of bed,” she said. “Everything seems to be a chore. Getting dressed is a chore. Taking a shower is a chore.”

She described stepping into the shower one morning and realizing she didn’t know what to do next. “So I went back to bed soaking wet.”

The light effect

Bartczak takes on the darkness with artificial light. She uses a prescribed light box in her bathroom while she gets ready for work in the morning. At her job as a legal secretary, she uses a Verilux Happy Light — not prescribed — in short bursts to giver her a little extra “pep,” she said. She bought it at Walgreens for $30.

“I think that it makes a difference,” the mother of three children said.

But Marty Sozansky, 65, isn’t sure if the therapy light she purchased five or six years ago makes a difference. That’s because she uses it as only one part of a full-frontal assault on the winter blahs. She also cuts way down on sugar and alcohol, eats more fruits and vegetables, maintains or increases her exercise and takes 1,000 IU (international units) of Vitamin D daily during the winter.

The battle has gotten harder over the years, she said. “I’ve lived in Duluth about 15 years, and as I’ve aged I’ve had more and more struggles in winter.”

Sozansky, an instructor in the Department of Writing Studies at the University of Minnesota Duluth, sits under a non-prescription therapy light every morning during the winter. But she also reads or studies something she enjoys. “That alone seems to start my day better,” she said.

Sozansky bought the therapy light for $90 one Saturday morning.

Prescription therapy lights can be considerably more expensive, but they also are covered under many insurance plans. Some research shows they help up to 60 to 75 percent of the people who use them, Lewandowski said. About 30 percent of his patients who use it “have pretty dramatic improvements,” he added.

Brain’s ‘light reader’

The bright light is designed to stimulate a part of the brain that is about the size of a grain of rice, Lewandowski said. The suprachiasmatic nucleus is the “light reader” that takes in light through the eye and translates the information to the pineal gland and the hypothalamus. They are the parts of the brain that regulate the sleep-wake cycle.

“In some animals, that part of the brain indicates when they should go into hibernation,” he said. “In other animals, it means store up carbohydrates and eat fats.”

But it’s not known why the process affects some people more than others, Lewandowski said. It affects more women than men — by 65 to 35 percent. Among those with SAD, 68 percent have a family history of it, and the families tend to be from northern climates.

Climate is a factor for Mistretta, 64, an Austin, Minn., native who returned to Minnesota after 32 years in Atlanta. She increases her Vitamin D intake in winter and uses a light box. But she is an active person and doesn’t like the recommended 30 to 45 minutes of use. “I don’t sit for 45 minutes,” she said.

m The light Mistretta uses is 10,000 lux, a measure of light intensity. Lewandowski said therapy lights should be in the range of 5,000 to 15,000 lux. By comparison, a standard home light bulb is 300 lux. Direct sunlight can be anywhere from 32,000 to 130,000 lux.

Greenwalt, who grew up on the Iron Range, lived in Kansas City and Las Vegas for most of the 1990s. She found the climate in those sunnier places well-suited to her. Since returning to the Northland in 1998, she has struggled through the winters.

“I kind of have an anti-Duluth body,” Greenwalt said.

The 42-year-old administrative assistant uses her light box for up to an hour, takes vitamins and continues to work out at the gym, although she said she almost fell asleep on the elliptical machine the other day.

She calls the effect of light therapy subtle. “They really say it works, but it doesn’t perform miracles.”

Mistretta, 64, agrees. There’s something that works much better, she said.

“I don’t think there’s any substitute for a blue sky.”

©2011 the Duluth News Tribune (Duluth, Minn.)

Visit the Duluth News Tribune (Duluth, Minn.) at www.duluthnewstribune.com

Distributed by MCT Information Services

-Angela Greenwalt blames Duluth.

"They should give out Prozac at the borders of Duluth," the Harbor Highlands resident said.

It's worse in Barnum, Bobbie Mistretta said.

"We live in what they call a moraine," the retiree said. "We get even less sun than in Duluth."

Greenwalt and Mistretta are among Northlanders who have begun their annual battle with SAD -- Seasonal Affective Disorder. As the days grow shorter, they're gripped by fatigue and lethargy. They fight back with Vitamin D, exercise, lifestyle changes and specially designed, extremely bright lights.

It's no illusion, said Tom Lewandowski, a psychotherapist at St. Luke's hospital and licensed independent social worker with expertise in SAD. The transition to winter acts as a depressant for many people, and it gets worse as you go north.

"In Florida, the incidence of SAD is about 1.4 percent, whereas in New Hampshire -- which is about the same latitude as Duluth -- it's around 10 percent," Lewandowski said. "It keeps increasing as you go north. It pretty much maxes out when

you get to Anchorage and Helsinki (Finland), and it can get as high as 15 percent."

Winter blues

Those numbers refer specifically to SAD, a clinical illness that accompanies other forms of depression, Lewandowski said. Many more Northlanders experience some degree of depressive symptoms around this time of year.

"You can have the winter blues, which probably affects 30 to 40 percent of the population," he said. "But usually that is a passing phase, usually at the onset of winter. Then it kind of fades. ... In clinical Seasonal Affective Disorder, that 'Oh no, the season's changing' keeps going and gets more intense."

That's how it works for Rachel Bartczak.

"In January and February you go to work and it's dark out and you come home and it's dark out," the Cloquet woman said. "You get through New Year's and there's nothing to look forward to."

Bartczak, 30, said she has battled depression since she was in high school.

"When I'm having a really bad day, when I'm feeling slummy, I don't want to get out of bed," she said. "Everything seems to be a chore. Getting dressed is a chore. Taking a shower is a chore."

She described stepping into the shower one morning and realizing she didn't know what to do next. "So I went back to bed soaking wet."

The light effect

Bartczak takes on the darkness with artificial light. She uses a prescribed light box in her bathroom while she gets ready for work in the morning. At her job as a legal secretary, she uses a Verilux Happy Light -- not prescribed -- in short bursts to giver her a little extra "pep," she said. She bought it at Walgreens for $30.

"I think that it makes a difference," the mother of three children said.

But Marty Sozansky, 65, isn't sure if the therapy light she purchased five or six years ago makes a difference. That's because she uses it as only one part of a full-frontal assault on the winter blahs. She also cuts way down on sugar and alcohol, eats more fruits and vegetables, maintains or increases her exercise and takes 1,000 IU (international units) of Vitamin D daily during the winter.

The battle has gotten harder over the years, she said. "I've lived in Duluth about 15 years, and as I've aged I've had more and more struggles in winter."

Sozansky, an instructor in the Department of Writing Studies at the University of Minnesota Duluth, sits under a non-prescription therapy light every morning during the winter. But she also reads or studies something she enjoys. "That alone seems to start my day better," she said.

Sozansky bought the therapy light for $90 one Saturday morning.

Prescription therapy lights can be considerably more expensive, but they also are covered under many insurance plans. Some research shows they help up to 60 to 75 percent of the people who use them, Lewandowski said. About 30 percent of his patients who use it "have pretty dramatic improvements," he added.

Brain's 'light reader'

The bright light is designed to stimulate a part of the brain that is about the size of a grain of rice, Lewandowski said. The suprachiasmatic nucleus is the "light reader" that takes in light through the eye and translates the information to the pineal gland and the hypothalamus. They are the parts of the brain that regulate the sleep-wake cycle.

"In some animals, that part of the brain indicates when they should go into hibernation," he said. "In other animals, it means store up carbohydrates and eat fats."

But it's not known why the process affects some people more than others, Lewandowski said. It affects more women than men -- by 65 to 35 percent. Among those with SAD, 68 percent have a family history of it, and the families tend to be from northern climates.

Climate is a factor for Mistretta, 64, an Austin, Minn., native who returned to Minnesota after 32 years in Atlanta. She increases her Vitamin D intake in winter and uses a light box. But she is an active person and doesn't like the recommended 30 to 45 minutes of use. "I don't sit for 45 minutes," she said.

m The light Mistretta uses is 10,000 lux, a measure of light intensity. Lewandowski said therapy lights should be in the range of 5,000 to 15,000 lux. By comparison, a standard home light bulb is 300 lux. Direct sunlight can be anywhere from 32,000 to 130,000 lux.

Greenwalt, who grew up on the Iron Range, lived in Kansas City and Las Vegas for most of the 1990s. She found the climate in those sunnier places well-suited to her. Since returning to the Northland in 1998, she has struggled through the winters.

"I kind of have an anti-Duluth body," Greenwalt said.

The 42-year-old administrative assistant uses her light box for up to an hour, takes vitamins and continues to work out at the gym, although she said she almost fell asleep on the elliptical machine the other day.

She calls the effect of light therapy subtle. "They really say it works, but it doesn't perform miracles."

Mistretta, 64, agrees. There's something that works much better, she said.

"I don't think there's any substitute for a blue sky."

©2011 the Duluth News Tribune (Duluth, Minn.)

Visit the Duluth News Tribune (Duluth, Minn.) at www.duluthnewstribune.com



Distributed by MCT Information Services

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Diabetes Screening Vital

Posted Nov 23, 2011

The South Florida medical community is making a pre-emptive strike on diabetes by encouraging people to get screened to see if they are at risk of developing the quiet killer.

“Diabetes is a silent killer,” said Dr. Joseph Gutman, a lead endocrinologist at Mount Sinai Medical Center in Miami Beach.

Diabetes is the seventh-leading cause of death in the country, according to the Centers for Disease Control and Prevention.

Gutman has specialized in diabetes for 27 years. In September he began “Test My Relatives,” a campaign to get family members of diabetic patients to have their blood sugar levels tested.

“What I want is to outreach in the community, to help people with diabetes and offer them treatment,” Gutman said.

A normal fasting blood glucose level is usually under 100mg/dl and diagnosis for diabetes is over 125mg/dl. A pre-diabetic’s blood sugar level lies in between 100 to 125mg/dl.

Pre-diabetes is an opportunity for people to modify their daily routine. All it takes is a nutritious diet, daily exercise and being vigilant about checking blood sugar levels.

Being pre-diabetic is not a sentencing — it is a warning. Treatment and lifestyle changes can prevent or delay the development of the debilitating disease.

But those at risk should be warned: pre-diabetes possesses a mean medical backhand. The condition is difficult to detect without getting screened.

Teddy Speropoulos is the director of the Memorial Diabetes and Nutrition Center in Hollywood. “Very often pre-diabetics will not have any symptoms. So if someone is at risk, testing is often the only way to get help,” he said.

The center, which treats about 300 patients a month, takes appointments for new patients from South Broward as long as they have a prescription.

James Washington, 59, is pre-diabetic. He was living a sedentary life and a frequent consumer of fast food when he arrived at the center.

“I thought the four-hour class was going to be boring but it was the best thing. Without them I might be dead — without their support and education,” Washington said.

Washington has a family history of diabetes — his uncle and cousin, both dead, suffered from it. After seven months at the center Washington said he lost 30 pounds, walks daily, eats fruits and vegetables, and checks his blood sugar levels.

“I exercise, walking three miles a day. I sleep a lot better. I couldn’t walk a mile when I first started,” Washington said.

Having a family history, poor diet, and a lack of exercise were all working against Washington.

Other characteristics that put someone at risk include high triglycerides, high blood pressure and polycystic ovary syndrome. Gutman said that someone with a family history and a body mass index over 30 has a 70 percent chance of being diagnosed with diabetes in their life.

Gestational diabetes or having a baby of more than nine pounds increases the risk of developing Type 2 diabetes. Diabetes America reports 40 percent of women with gestational diabetes will develop Type 2 in five to 10 years.

Ethnic groups such as African Americans, Hispanic Americans, Asian Americans, and Native Americans are at a higher risk. The skin condition Acanthosis nigricans, a darkening and thickening of the skin in its own folds and creases, is an indicator unique to Type 2 diabetes.

Dr. Luis Gonzalez-Mendoza, head of endocrinology at Miami Children’s Hospital, says Type 1 and Type 2 diabetes manifest differently. Contracting Type 1 is not related to daily life, although unhealthy habits can worsen its progression. Type 1 is an innate disease in which the body stops producing insulin.

“In Type 1 there is very little you can do. It has nothing to do with lifestyle,” he said.

People can still be screened for Type 1. Researchers have been able to identify biochemical antibodies that indicates someone is at risk for developing Type 1.

The detection of one antibody means the patient has a less than 25 percent chance of developing Type 1 diabetes within five years. Two antibodies increase the percentage to between 25 and 49 percent. Three or more antibodies and the risk of contracting Type 1 diabetes is greater than 50 percent, according to Della Matheson, trial coordinator at the University of Miami Diabetes Research Institute for the Type 1 diabetes study.

“It’s an aggregate risk,” said Matheson, “Additional testing will also help to better define the risk categories.”

For Type 1 diabetics, screening and education could mean the difference between sleeping in your own bed or a hospital bed.

Allen Dray, a research scientist at the Florida Department of Agriculture, had a close call with his eldest daughter Evie, 13 years ago. She had been feeling fatigued and thirsty when Dray took her to the doctor and found out she was a Type 1 diabetic. The disease had been uncontrolled for so long she had to be admitted for 11 days.

Dray doesn’t have a family history of diabetes and his wife was adopted. Their three other children were screened and their youngest, Rebecca, was found to be at moderate risk. Dr. Jay Skyler, professor and deputy director of the Diabetes Research Institute at the Miller School of Medicine at UM, detected at least two of the biochemical antibodies in her bloodstream.

Rebecca grew up watching her older sister manage her diabetes and joined an oral insulin study at the Diabetes Research Institute between 2000 and 2003. Rebecca, now 14, was diagnosed for Type 1 diabetes in June. She gives herself insulin shots and checks her blood sugar.

“The difference between our experience with Evie and our experience with Rebecca has just been tremendous. It’s just the education process of being ready or not,” Dray said.

For potential Type 2 diabetes patients, changing your lifestyle to incorporate healthy eating habits and doing more exercise can significantly reduce your risk of contracting the disease.

Dr. Ronald Goldberg, associate director of medical affairs at the Diabetes Research Institute at UM, helped conduct a study through the Diabetes Prevention Program comparing lifestyle intervention with metformin treatment. Metformin is a capsule taken to control blood sugar levels.

Lifestyle intervention participants took education classes, had regulated diets and increased physical activity by 150 minutes per week. They reduced the risk for Type 2 diabetes by 58 percent while metformin reduced the risk by only 31 percent.

Goldberg and Skyler believe early detection and diagnosis is the key to arming patients.

“The greatest benefit you’re going to have is proportionate to how early on you can prevent this disease,” Goldberg said.

©2011 The Miami Herald

Visit The Miami Herald at www.miamiherald.com

The South Florida medical community is making a pre-emptive strike on diabetes by encouraging people to get screened to see if they are at risk of developing the quiet killer.

"Diabetes is a silent killer," said Dr. Joseph Gutman, a lead endocrinologist at Mount Sinai Medical Center in Miami Beach.

Diabetes is the seventh-leading cause of death in the country, according to the Centers for Disease Control and Prevention.

Gutman has specialized in diabetes for 27 years. In September he began "Test My Relatives," a campaign to get family members of diabetic patients to have their blood sugar levels tested.

"What I want is to outreach in the community, to help people with diabetes and offer them treatment," Gutman said.

A normal fasting blood glucose level is usually under 100mg/dl and diagnosis for diabetes is over 125mg/dl. A pre-diabetic's blood sugar level lies in between 100 to 125mg/dl.

Pre-diabetes is an opportunity for people to modify their daily routine. All it takes is a nutritious diet, daily exercise and being vigilant about checking blood sugar levels.

Being pre-diabetic is not a sentencing -- it is a warning. Treatment and lifestyle changes can prevent or delay the development of the debilitating disease.

But those at risk should be warned: pre-diabetes possesses a mean medical backhand. The condition is difficult to detect without getting screened.

Teddy Speropoulos is the director of the Memorial Diabetes and Nutrition Center in Hollywood. "Very often pre-diabetics will not have any symptoms. So if someone is at risk, testing is often the only way to get help," he said.

The center, which treats about 300 patients a month, takes appointments for new patients from South Broward as long as they have a prescription.

James Washington, 59, is pre-diabetic. He was living a sedentary life and a frequent consumer of fast food when he arrived at the center.

"I thought the four-hour class was going to be boring but it was the best thing. Without them I might be dead -- without their support and education," Washington said.

Washington has a family history of diabetes -- his uncle and cousin, both dead, suffered from it. After seven months at the center Washington said he lost 30 pounds, walks daily, eats fruits and vegetables, and checks his blood sugar levels.

"I exercise, walking three miles a day. I sleep a lot better. I couldn't walk a mile when I first started," Washington said.

Having a family history, poor diet, and a lack of exercise were all working against Washington.

Other characteristics that put someone at risk include high triglycerides, high blood pressure and polycystic ovary syndrome. Gutman said that someone with a family history and a body mass index over 30 has a 70 percent chance of being diagnosed with diabetes in their life.

Gestational diabetes or having a baby of more than nine pounds increases the risk of developing Type 2 diabetes. Diabetes America reports 40 percent of women with gestational diabetes will develop Type 2 in five to 10 years.

Ethnic groups such as African Americans, Hispanic Americans, Asian Americans, and Native Americans are at a higher risk. The skin condition Acanthosis nigricans, a darkening and thickening of the skin in its own folds and creases, is an indicator unique to Type 2 diabetes.

Dr. Luis Gonzalez-Mendoza, head of endocrinology at Miami Children's Hospital, says Type 1 and Type 2 diabetes manifest differently. Contracting Type 1 is not related to daily life, although unhealthy habits can worsen its progression. Type 1 is an innate disease in which the body stops producing insulin.

"In Type 1 there is very little you can do. It has nothing to do with lifestyle," he said.

People can still be screened for Type 1. Researchers have been able to identify biochemical antibodies that indicates someone is at risk for developing Type 1.

The detection of one antibody means the patient has a less than 25 percent chance of developing Type 1 diabetes within five years. Two antibodies increase the percentage to between 25 and 49 percent. Three or more antibodies and the risk of contracting Type 1 diabetes is greater than 50 percent, according to Della Matheson, trial coordinator at the University of Miami Diabetes Research Institute for the Type 1 diabetes study.

"It's an aggregate risk," said Matheson, "Additional testing will also help to better define the risk categories."

For Type 1 diabetics, screening and education could mean the difference between sleeping in your own bed or a hospital bed.

Allen Dray, a research scientist at the Florida Department of Agriculture, had a close call with his eldest daughter Evie, 13 years ago. She had been feeling fatigued and thirsty when Dray took her to the doctor and found out she was a Type 1 diabetic. The disease had been uncontrolled for so long she had to be admitted for 11 days.

Dray doesn't have a family history of diabetes and his wife was adopted. Their three other children were screened and their youngest, Rebecca, was found to be at moderate risk. Dr. Jay Skyler, professor and deputy director of the Diabetes Research Institute at the Miller School of Medicine at UM, detected at least two of the biochemical antibodies in her bloodstream.

Rebecca grew up watching her older sister manage her diabetes and joined an oral insulin study at the Diabetes Research Institute between 2000 and 2003. Rebecca, now 14, was diagnosed for Type 1 diabetes in June. She gives herself insulin shots and checks her blood sugar.

"The difference between our experience with Evie and our experience with Rebecca has just been tremendous. It's just the education process of being ready or not," Dray said.

For potential Type 2 diabetes patients, changing your lifestyle to incorporate healthy eating habits and doing more exercise can significantly reduce your risk of contracting the disease.

Dr. Ronald Goldberg, associate director of medical affairs at the Diabetes Research Institute at UM, helped conduct a study through the Diabetes Prevention Program comparing lifestyle intervention with metformin treatment. Metformin is a capsule taken to control blood sugar levels.

Lifestyle intervention participants took education classes, had regulated diets and increased physical activity by 150 minutes per week. They reduced the risk for Type 2 diabetes by 58 percent while metformin reduced the risk by only 31 percent.

Goldberg and Skyler believe early detection and diagnosis is the key to arming patients.

"The greatest benefit you're going to have is proportionate to how early on you can prevent this disease," Goldberg said.

©2011 The Miami Herald



Visit The Miami Herald at www.miamiherald.com

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Be Vitamin B12 Aware

Posted Nov 7, 2011

Vitamin B12 is important, and many people over 50 have a deficiency of this essential nutrient. There are a number of reasons for it. The most serious is pernicious anemia, caused by the lack of a protein that’s required for the body to absorb B12. The most common reason is ‘Atrophic gastritis,’ a condition where the lining of the stomach gets thinner as we age. It’s estimated that atrophic gastritis affects as many as one third of people over 50. Heavy use of anti-acid drugs can also affect the absorption of B12, as can gastric bypass surgery.

Symptoms of a mild deficiency may include irritability, problems with concentration, dizziness and fatigue, diarrhea, weight loss and easy bruising; though many mild cases have no symptoms at all. But as the deficiency gets more severe, it causes more serious symptoms. They include depression, confusion and memory loss; as well as problems with balance and tingling or numbness in fingers and toes. If the deficiency isn’t diagnosed and cured by B12 supplements, it can progress to actual dementia.

Because the symptoms can be so severe, some physicians miss the diagnosis of a simple vitamin deficiency that’s easily cured by a shot or a pill of the nutrient, taken with the total B factor. But it’s essential to get a quick and accurate diagnosis, because some recent studies are showing that a B12 deficiency may be connected with the onset and cause of Alzheimer’s disease. Numerous other studies show that an absence of this nutrient is also involved with the onset of clinical depression; a common problem in boomers and seniors.

Those over 50 who are vegetarians are at particular risk, because B12 is found mostly in animal-based foods such as meat, milk, eggs, poultry and fish. Those who eat none of these foods should supplement their diets with the full B factor in pill form.

If there’s any suspicion that you or someone you know may be suffering from a lack of B12, an easy and inexpensive blood test can determine the amount of this nutrient in the body. It’s important to know that even a very small deficiency can cause problems; some of which are even more serious than mental disturbances. B12 helps keep the amount of the amino acid homocysteine in balance, a function that may help lower the risk of heart disease.

Since a B12 deficiency is so much more common that most people realize, it’s a good idea to take a proactive stance by consuming a daily supplement of the full B complex, which will include B12. The B complex is totally interactive; all factors need to be included for any part of the vitamin to be absorbed.

But for those over 50, a blood screening in addition to supplementation is an ideal way to determine if you have enough vitamin B12 to keep your brain in good shape.

Wina Sturgeon is an active boomer based in Salt Lake City who mountain bikes, skates on both ice blades and wheels, lifts weights and runs to stay in shape.

© 2011, Adventure Sports Weekly (adventuresportsweekly.com)

Vitamin B12 is important, and many people over 50 have a deficiency of this essential nutrient. There are a number of reasons for it. The most serious is pernicious anemia, caused by the lack of a protein that's required for the body to absorb B12. The most common reason is 'Atrophic gastritis,' a condition where the lining of the stomach gets thinner as we age. It's estimated that atrophic gastritis affects as many as one third of people over 50. Heavy use of anti-acid drugs can also affect the absorption of B12, as can gastric bypass surgery.

Symptoms of a mild deficiency may include irritability, problems with concentration, dizziness and fatigue, diarrhea, weight loss and easy bruising; though many mild cases have no symptoms at all. But as the deficiency gets more severe, it causes more serious symptoms. They include depression, confusion and memory loss; as well as problems with balance and tingling or numbness in fingers and toes. If the deficiency isn't diagnosed and cured by B12 supplements, it can progress to actual dementia.

Because the symptoms can be so severe, some physicians miss the diagnosis of a simple vitamin deficiency that's easily cured by a shot or a pill of the nutrient, taken with the total B factor. But it's essential to get a quick and accurate diagnosis, because some recent studies are showing that a B12 deficiency may be connected with the onset and cause of Alzheimer's disease. Numerous other studies show that an absence of this nutrient is also involved with the onset of clinical depression; a common problem in boomers and seniors.

Those over 50 who are vegetarians are at particular risk, because B12 is found mostly in animal-based foods such as meat, milk, eggs, poultry and fish. Those who eat none of these foods should supplement their diets with the full B factor in pill form.

If there's any suspicion that you or someone you know may be suffering from a lack of B12, an easy and inexpensive blood test can determine the amount of this nutrient in the body. It's important to know that even a very small deficiency can cause problems; some of which are even more serious than mental disturbances. B12 helps keep the amount of the amino acid homocysteine in balance, a function that may help lower the risk of heart disease.

Since a B12 deficiency is so much more common that most people realize, it's a good idea to take a proactive stance by consuming a daily supplement of the full B complex, which will include B12. The B complex is totally interactive; all factors need to be included for any part of the vitamin to be absorbed.

But for those over 50, a blood screening in addition to supplementation is an ideal way to determine if you have enough vitamin B12 to keep your brain in good shape.

Wina Sturgeon is an active boomer based in Salt Lake City who mountain bikes, skates on both ice blades and wheels, lifts weights and runs to stay in shape.

© 2011, Adventure Sports Weekly (adventuresportsweekly.com)

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Mexico Dealing with Childhood Obesity Too

Posted October 27, 2011

MEXICO CITY – Anghella Torres is just 4 years old, but already she weighs 66 pounds (30 kilos) – twice what she should. Because of her excess girth, her little feet constantly hurt from bearing the extra weight.

Anghella knows she is obese and she doesn’t like it. And now, even though she doesn’t know how to read or count calories, she is on a diet. With the help of her grandmother and caretaker, Elizabeth Sucilla, Anghella is following a modest diet and exercise program established for her by a nurse at a local public hospital earlier this year.

“I have to stop eating candies,” she said.

Her new regimen also requires her to cut down on the deep-fried potato wedges she ate every other day in the streets and spoonfuls of heavy cream she downed like yogurt.

Mexico, which claims to have the fattest children in the world, is trying to encourage others to follow Anghella’s lead. Public schools have banned junk food and are requiring more hours of physical education while the federal government has launched a media campaign that invites families to enroll their kids in a public weight-loss program.

Yet three-quarters of Mexico City’s 2,400 public schools don’t have playgrounds or gyms for exercise. And 80 percent of the schools don’t have water fountains. Experts stress the importance of drinking more water and fewer sugary drinks to prevent and reverse weight gain.

President Felipe Calderon said earlier this year that Mexico had the highest rate of obesity for children ages 5 to 19 in the world. And although he did not cite any source, University of North Carolina nutrition professor Barry Popkin, who has studied childhood obesity in many countries, agrees that it “is the highest I know of in the world.”

While a large number of children in Mexico’s poor, rural villages are still underweight, the country as a whole has seen the second-fastest growth rate for childhood obesity of nine countries examined by Popkin in a 2007 study, including the United States. The fastest growth rate of the nine is in Australia, according to the study, which compares health statistics in the countries over the past two decades.

The problem in Mexico is especially pronounced in the capital, Mexico City, and near the U.S.-Mexico border, according to a study by Mexico’s National Institute of Public Health.

Children and teenagers make up Mexico’s largest age group, representing 39 percent of the country’s 112 million people. More than 28 percent of children between 5 and 9, and 38 percent of preteens and teenagers ages 10 to 19, are overweight or obese, according to statistics from the Mexican Social Security Institute.

In the U.S., the Centers for Disease Control and Prevention says 12.5 million, or 17 percent, of children and adolescents ages 2 to 19 are obese. First lady Michelle Obama has tackled the issue with her “Let’s Move” campaign, pushing for better school lunches, more access to fruits and vegetables and more physical activity. And Congress last year passed a new law requiring school lunches to be healthier.

In Brazil, a newly industrialized nation like Mexico, 19 percent of children ages 5 to 9 are overweight, and 15 percent are obese, according to government statistics. Officials did not have statistics available for teenagers.

Mexico’s public health institute says the problem lies not just with children: Seventy percent of Mexican adults are overweight or obese as well. Officials have decided to target children and teens first, however, because they are the largest age group and fighting their habits now would prevent large numbers of diabetes cases and other illnesses in the future, the officials said.

“The earlier obesity shows up, the higher the risk the kid will become an obese adult and contract other diseases like diabetes, hypertension,” said Leticia Martinez, chief nutritionist for Mexico’s public health institute. “We see this as an emergency.”

Health officials define obesity as having too much body fat. In Mexico, the U.S. and elsewhere, obesity is determined through BMI, a measure of body fat based on height and weight.

Mexico’s childhood obesity spans social classes, though the poor are less informed and equipped to deal with the epidemic.

Starting this year, pre-kindergarten and elementary schools completely banned the sale of soft drinks and junk food and replaced previous breakfast programs with dishes rich in vegetables, such as squash blossoms and carrots. Middle schools are only selling sugar-free drinks, low-calorie snacks and small bags of chips that appear in new food guidelines approved by the departments of health and education.

During recess at the Republica Italiana elementary school, children run out of classrooms and form three lines, each one of which leads to a different food option.

Their choices include a turkey hot dog on a wheat bun with tomatoes and no mayonnaise; “nopales,” or edible cactus paddles, with sliced peppers on a corn tortilla; sunflower seeds or a scoop of unsweetened lemon sorbet; and slices of cucumbers and carrots.

Principal Yamile Bobadilla says there’s nothing she can do about vendors who still gather outside of the school gates to sell sodas, greasy pizzas and chips.

Some of the children, and even some parents, have complained about the junk food ban, she said, adding, “They see me as the witch.”

The country’s healthy-weight campaign has other challenges: Officials acknowledge there aren’t enough dietitians in the public schools to help all of the children in need. They also note a prevailing cultural notion that a chubby baby is a healthy baby.

“Any efforts to improve the school environment are very important to combat the epidemic,” said Chessa Lutter, a regional adviser on food and nutrition for the Pan American Health Organization.

Starting in the 2010-2011 school year, education officials began increasing the number of physical education hours from one to three per week based on their conclusion that some children are obese because they don’t exercise. On a recent morning at Republica Italiana, several groups of kids were sent out to the school yard to run, play softball or twirl hula-hoops.

Bobadilla said some children still faint and suffer from extreme fatigue because of their weight problems.

Guillermo Ayala, who leads the food guidelines’ task force at the Education Department, also heads an effort to have every child in Mexico City weighed and measured by a team of physical education coaches and nurses. Schools with a high number of children who have gained or not lost weight will face administrative sanctions, he said.

Outside the classroom, government-sponsored TV spots show kids struggling under heavy sacks of grain, symbols of the extra pounds (kilos) many are carrying around with them. The ads invite parents to enroll their children in a government-run program of diet and exercise. About 5.3 million children participate every year, but officials don’t keep track of how many of them are overweight.

Anghella’s grandmother Sucilla took her to a public hospital in May at the suggestion of the girl’s day care providers, who said something would have to be done about the child’s diet and exercise before she started school in August.

A nurse at the hospital suggested that Anghella start taking regular walks, drinking a lot of water and eating more whole grains, vegetables and fruits.

She goes often to visit the nurse, who weighs her regularly.

At home, when her small hand tries to reach for a sweet roll on the table, Sucilla slaps it and says, “You know why, my little girl.”

Anghella said she doesn’t like it when adults say she’s fat.

“No, sweetheart. You are cuddly,” Sucilla tells her. But she then adds, “I worry because I don’t want my little girl to be an obese girl.”

MEXICO CITY - Anghella Torres is just 4 years old, but already she weighs 66 pounds (30 kilos) - twice what she should. Because of her excess girth, her little feet constantly hurt from bearing the extra weight.

Anghella knows she is obese and she doesn't like it. And now, even though she doesn't know how to read or count calories, she is on a diet. With the help of her grandmother and caretaker, Elizabeth Sucilla, Anghella is following a modest diet and exercise program established for her by a nurse at a local public hospital earlier this year.

"I have to stop eating candies," she said.

Her new regimen also requires her to cut down on the deep-fried potato wedges she ate every other day in the streets and spoonfuls of heavy cream she downed like yogurt.

Mexico, which claims to have the fattest children in the world, is trying to encourage others to follow Anghella's lead. Public schools have banned junk food and are requiring more hours of physical education while the federal government has launched a media campaign that invites families to enroll their kids in a public weight-loss program.

Yet three-quarters of Mexico City's 2,400 public schools don't have playgrounds or gyms for exercise. And 80 percent of the schools don't have water fountains. Experts stress the importance of drinking more water and fewer sugary drinks to prevent and reverse weight gain.

President Felipe Calderon said earlier this year that Mexico had the highest rate of obesity for children ages 5 to 19 in the world. And although he did not cite any source, University of North Carolina nutrition professor Barry Popkin, who has studied childhood obesity in many countries, agrees that it "is the highest I know of in the world."

While a large number of children in Mexico's poor, rural villages are still underweight, the country as a whole has seen the second-fastest growth rate for childhood obesity of nine countries examined by Popkin in a 2007 study, including the United States. The fastest growth rate of the nine is in Australia, according to the study, which compares health statistics in the countries over the past two decades.

The problem in Mexico is especially pronounced in the capital, Mexico City, and near the U.S.-Mexico border, according to a study by Mexico's National Institute of Public Health.

Children and teenagers make up Mexico's largest age group, representing 39 percent of the country's 112 million people. More than 28 percent of children between 5 and 9, and 38 percent of preteens and teenagers ages 10 to 19, are overweight or obese, according to statistics from the Mexican Social Security Institute.

In the U.S., the Centers for Disease Control and Prevention says 12.5 million, or 17 percent, of children and adolescents ages 2 to 19 are obese. First lady Michelle Obama has tackled the issue with her "Let's Move" campaign, pushing for better school lunches, more access to fruits and vegetables and more physical activity. And Congress last year passed a new law requiring school lunches to be healthier.

In Brazil, a newly industrialized nation like Mexico, 19 percent of children ages 5 to 9 are overweight, and 15 percent are obese, according to government statistics. Officials did not have statistics available for teenagers.

Mexico's public health institute says the problem lies not just with children: Seventy percent of Mexican adults are overweight or obese as well. Officials have decided to target children and teens first, however, because they are the largest age group and fighting their habits now would prevent large numbers of diabetes cases and other illnesses in the future, the officials said.

"The earlier obesity shows up, the higher the risk the kid will become an obese adult and contract other diseases like diabetes, hypertension," said Leticia Martinez, chief nutritionist for Mexico's public health institute. "We see this as an emergency."

Health officials define obesity as having too much body fat. In Mexico, the U.S. and elsewhere, obesity is determined through BMI, a measure of body fat based on height and weight.

Mexico's childhood obesity spans social classes, though the poor are less informed and equipped to deal with the epidemic.

Starting this year, pre-kindergarten and elementary schools completely banned the sale of soft drinks and junk food and replaced previous breakfast programs with dishes rich in vegetables, such as squash blossoms and carrots. Middle schools are only selling sugar-free drinks, low-calorie snacks and small bags of chips that appear in new food guidelines approved by the departments of health and education.

During recess at the Republica Italiana elementary school, children run out of classrooms and form three lines, each one of which leads to a different food option.

Their choices include a turkey hot dog on a wheat bun with tomatoes and no mayonnaise; "nopales," or edible cactus paddles, with sliced peppers on a corn tortilla; sunflower seeds or a scoop of unsweetened lemon sorbet; and slices of cucumbers and carrots.

Principal Yamile Bobadilla says there's nothing she can do about vendors who still gather outside of the school gates to sell sodas, greasy pizzas and chips.

Some of the children, and even some parents, have complained about the junk food ban, she said, adding, "They see me as the witch."

The country's healthy-weight campaign has other challenges: Officials acknowledge there aren't enough dietitians in the public schools to help all of the children in need. They also note a prevailing cultural notion that a chubby baby is a healthy baby.

"Any efforts to improve the school environment are very important to combat the epidemic," said Chessa Lutter, a regional adviser on food and nutrition for the Pan American Health Organization.

Starting in the 2010-2011 school year, education officials began increasing the number of physical education hours from one to three per week based on their conclusion that some children are obese because they don't exercise. On a recent morning at Republica Italiana, several groups of kids were sent out to the school yard to run, play softball or twirl hula-hoops.

Bobadilla said some children still faint and suffer from extreme fatigue because of their weight problems.

Guillermo Ayala, who leads the food guidelines' task force at the Education Department, also heads an effort to have every child in Mexico City weighed and measured by a team of physical education coaches and nurses. Schools with a high number of children who have gained or not lost weight will face administrative sanctions, he said.

Outside the classroom, government-sponsored TV spots show kids struggling under heavy sacks of grain, symbols of the extra pounds (kilos) many are carrying around with them. The ads invite parents to enroll their children in a government-run program of diet and exercise. About 5.3 million children participate every year, but officials don't keep track of how many of them are overweight.

Anghella's grandmother Sucilla took her to a public hospital in May at the suggestion of the girl's day care providers, who said something would have to be done about the child's diet and exercise before she started school in August.

A nurse at the hospital suggested that Anghella start taking regular walks, drinking a lot of water and eating more whole grains, vegetables and fruits.

She goes often to visit the nurse, who weighs her regularly.

At home, when her small hand tries to reach for a sweet roll on the table, Sucilla slaps it and says, "You know why, my little girl."

Anghella said she doesn't like it when adults say she's fat.

"No, sweetheart. You are cuddly," Sucilla tells her. But she then adds, "I worry because I don't want my little girl to be an obese girl."

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Why People Start and Stop Smoking

Posted Sept 27, 2011

Mike Johnston has no idea> what he was thinking when he took up cigarettes at age 15

“I was definitely more impulsive back then than I am now,” said Johnston, 39, of Oakville, Mo., as he puffed away on a downtown sidewalk during a work break. “I was young and had no responsibilities. Now I have a wife and two kids.”

Charlie Condor, 49, of St. John, Mo., was smoking with co-workers when he admitted that his lifestyle and woeful views about life might have played a role in his decision to start smoking 28 years ago.

“Just kid stuff, you know? I was coming up through adulthood and it seemed like life was against me,” he said.

The way that Johnston and Condor assess their younger selves mirrors recent findings of two researchers at University of Missouri.

By analyzing data collected during a long-term study, Andrew K. Littlefield, doctoral student in psychology, and Kenneth J. Sher, professor of psychology, have found that people who smoke at age 18 have higher rates of impulsivity than non-smokers at that age. They’ve also found that those who quit between ages 18 and 25 show the biggest decreases in impulsivity during that time period.

The study, which began in 1987 with one group of 489 Mizzou students and has continued with several more groups, is intended to assess substance use in general, not just smoking, according to Littlefield.

Among other things, subjects are asked to rate how well two statements describe their behaviors on a scale of one to 10. The statements pertain to whether they tend to think through facts, details and consequences before deciding to do something and whether they tend to worry a lot.

They are surveyed seven times – once a year during college then at about age 25, 29 and 35.

“We see the biggest changes in impulsivity and neuroticism between age 18 and 25,” Littlefield said. “After age 30, most personality traits are usually set in plaster and they’re not changing much.”

Changes in people ages 18 to 25 begin happening when they leave their families, go to college, enter the workforce, get married and have children. Logic would dictate that becoming less impulsive and neurotic are a part of maturing, which causes many smokers to quit.

But Littlefield and other scientists aren’t ready to draw that conclusion yet.

Quitting smoking might be prompting the changes in personality traits, he said. He stressed, however, that he means personality changes over a long time frame, not short-term ones like nervousness and lower self-regulation that come from nicotine withdrawals.

Littlefield and Sher have also concluded that, by the time a person is 35, smoking is usually no longer related to neuroticism and impulsivity.

“Now, it’s moving from those traits to addiction and compulsivity, which is when your behaviors are patterns,” Littlefield said. “You’re on autopilot, lighting up without thinking when you get out of bed or on the way to work.”

He believes the findings of his study could be useful in figuring out ways to help people quit smoking before it becomes addictive and compulsive.

Studies have shown, he said, that “there are residual effects when you follow up with students after they’ve taken a money management course. You find that many of them reduce drinking and either quit or reduce smoking. They not only spend less, but they reduce behaviors associated with high impulsivity.”

He urges people to think of self-regulation as a muscle. It can become fatigued if you use it too much, or it can grow stronger when exercised.

“Likewise,” he added, “if you can target internal thoughts you can make them more positive and reduce the impact of being neurotic.”

Mike Johnston has no idea> what he was thinking when he took up cigarettes at age 15

"I was definitely more impulsive back then than I am now," said Johnston, 39, of Oakville, Mo., as he puffed away on a downtown sidewalk during a work break. "I was young and had no responsibilities. Now I have a wife and two kids."

Charlie Condor, 49, of St. John, Mo., was smoking with co-workers when he admitted that his lifestyle and woeful views about life might have played a role in his decision to start smoking 28 years ago.

"Just kid stuff, you know? I was coming up through adulthood and it seemed like life was against me," he said.

The way that Johnston and Condor assess their younger selves mirrors recent findings of two researchers at University of Missouri.

By analyzing data collected during a long-term study, Andrew K. Littlefield, doctoral student in psychology, and Kenneth J. Sher, professor of psychology, have found that people who smoke at age 18 have higher rates of impulsivity than non-smokers at that age. They've also found that those who quit between ages 18 and 25 show the biggest decreases in impulsivity during that time period.

The study, which began in 1987 with one group of 489 Mizzou students and has continued with several more groups, is intended to assess substance use in general, not just smoking, according to Littlefield.

Among other things, subjects are asked to rate how well two statements describe their behaviors on a scale of one to 10. The statements pertain to whether they tend to think through facts, details and consequences before deciding to do something and whether they tend to worry a lot.

They are surveyed seven times - once a year during college then at about age 25, 29 and 35.

"We see the biggest changes in impulsivity and neuroticism between age 18 and 25," Littlefield said. "After age 30, most personality traits are usually set in plaster and they're not changing much."

Changes in people ages 18 to 25 begin happening when they leave their families, go to college, enter the workforce, get married and have children. Logic would dictate that becoming less impulsive and neurotic are a part of maturing, which causes many smokers to quit.

But Littlefield and other scientists aren't ready to draw that conclusion yet.

Quitting smoking might be prompting the changes in personality traits, he said. He stressed, however, that he means personality changes over a long time frame, not short-term ones like nervousness and lower self-regulation that come from nicotine withdrawals.

Littlefield and Sher have also concluded that, by the time a person is 35, smoking is usually no longer related to neuroticism and impulsivity.

"Now, it's moving from those traits to addiction and compulsivity, which is when your behaviors are patterns," Littlefield said. "You're on autopilot, lighting up without thinking when you get out of bed or on the way to work."

He believes the findings of his study could be useful in figuring out ways to help people quit smoking before it becomes addictive and compulsive.

Studies have shown, he said, that "there are residual effects when you follow up with students after they've taken a money management course. You find that many of them reduce drinking and either quit or reduce smoking. They not only spend less, but they reduce behaviors associated with high impulsivity."

He urges people to think of self-regulation as a muscle. It can become fatigued if you use it too much, or it can grow stronger when exercised.

"Likewise," he added, "if you can target internal thoughts you can make them more positive and reduce the impact of being neurotic."

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More Gluten Free Menu Options

Posted Sept 16, 2011

Eating at a restaurant can be a challenge for anyone on a restricted diet.

But when eating the wrong food can make you sick, eating out can be become downright scary.

Getting sick from food is a real possibility for the growing number of Americans who have celiac disease.

People with celiac disease have an intolerance to gluten, a protein found in wheat, barley and rye. It is considered the most under-diagnosed disease in the country, and it may affect one out of every 133 Americans, according to the Gluten Intolerance Group of North America, a national support group.

In addition, many more people have found that they have a sensitivity to wheat and/or gluten. Others have chosen not to eat wheat or gluten for various reasons. Some say they feel better without it; others think it helps with weight loss.

In the past, eating out has been difficult for anyone on a gluten-free diet. In carb-crazy, wheat-loving America, sometimes a salad might be the only thing on the menu that doesn’t use flour, bread, pasta or something else with gluten. And many times that salad comes with croutons.

Thomas Manning, a Forsyth County native who lives in North Raleigh, remembers eating out six years ago after he first found out he had celiac disease. Often, after he explained his situation, restaurant employees would become scared to serve him, worried that any mistake might make him sick. And many times when they did serve him, they’d offer nothing beyond a plain grilled chicken breast and a salad. “I got so tired of chicken breast and salad,” he said.

But now restaurants are starting to listen to — and welcome — the increasing numbers of diners who avoid wheat and gluten.

“There are a lot more restaurants that offer gluten-free options,” said Debbie Fisher of Clemmons, who also has celiac disease. “And the gluten-free menus have a lot more items on them.”

When Martha Russell learned she had celiac disease in 2003, “some people didn’t even know what gluten is,” she said. “Chefs are so much more aware of this now. And they love the challenge of creating something different for you.”

The Gluten Intolerance Group (www.gluten.net) has enrolled 1,620 restaurants in the country in its Gluten-Free Restaurant Awareness Program. In Winston-Salem, several restaurants now offer gluten-free options.

Extensive gluten-free menus are offered at such chains as Bonefish Grill, Carrabba’s Italian Grill, Firebirds Wood Fired Grill, Outback Steak House and Village Tavern, and at such independent restaurants as New Town Bistro and River Birch Lodge.

Jason’s Deli, a chain based in Texas with a location on Hanes Mall Boulevard, offers sandwiches on gluten-free bread. Mellow Mushroom and Brixx Wood Fired Pizza both offer gluten-free pizza.

Serving gluten-free meals is not as simple as removing or replacing the bread or pasta.

The gluten from wheat, barley and rye show up — or rather hide — in many ingredients.

“I’m very skeptical about any sauce or salad dressing,” said Fran Fox, because those often use flour for thickening. Fox, who has been gluten-free for 25 years, said it does require asking a lot of questions at restaurants.

Another hidden ingredient is soy sauce, which usually contains wheat. Other ingredients, such as malted barley, lurk in many processed foods.

Russell and others tend to stay away from Chinese and other Asian restaurants that use soy sauce. They often feel more comfortable in Mexican and Indian restaurants that do not rely heavily on wheat.

But it’s not just the ingredients. Cross-contamination poses a danger, too. Vegetables chopped on the same cutting board as a loaf of bread can contaminate someone’s salad and make them sick.

Similarly, the cook who makes a salad with croutons and then makes a gluten-free salad can contaminate the gluten-free salad.

At New Town Bistro, chef Donny Smith pulls out a clean cutting board and clean utensils when someone orders a gluten-free item.

“It’s not the best thing at 7 p.m. on a Saturday night, but there’s no other way around it,” Smith said. “It just becomes part of our job. We want to make sure people didn’t use tongs to grab bread out of the oven, then use it to grab a gluten-free entree.”

At Mellow Mushroom, general manager Margaret Waters said the staff changes aprons, washes hands and moves to a separate work area after receiving an order for a gluten-free pizza.

“We even have a different cart of ingredients — toppings, the sauce, the cheese — that we keep separate from everything else,” she said. And the pizza is put on a special rack so it does not touch the same oven surfaces that the regular pizzas touch.

When someone orders a gluten-free sandwich at Jason’s Deli, “only the managers are allowed to make it,” said supervisor Nancy Hernandez. “We make it in the back of the restaurant. We get all of the ingredients fresh from the back. We don’t use anything from the line” that might have come in contact with regular bread.

A plain piece of meat might seem like a safe choice, but not if it’s grilled on the same spot as grilled bread. Chef Travis Myers of River Birch Lodge sautes meats on his gluten-free menu in clean pans instead of grilling them.

Myers cooks all of his breaded and other gluten foods in one deep fryer, dedicating a second fryer to gluten-free items. “We can do french fries and (homemade potato) chips and not worry about cross-contamination,” he said.

Myers has a gluten-free menu of five appetizers, five salads, four sandwiches, eight entrees and three desserts.

In some cases, he has made an item gluten-free simply by removing the gluten ingredient. For instance, the seared tuna appetizer comes with pickled ginger but without the usual ginger sauce, which is made with soy sauce.

“Once we dove into the nuts and bolts of it, it was easy to make things gluten-free, because we make most things in-house,” Myers said. >

River Birch has offered a gluten-free menu longer than most — about six years. “Our lawyer’s family is gluten-intolerant, so that’s how we learned about it,” he said.

“Word of mouth has really helped us. Now I’d say one out of every five tables we’re getting a gluten-free order. A lot of times we’ll have a whole party of gluten-free.”

That was the case last Thursday when about a dozen members of the local Gluten Intolerance Group ate lunch at River Birch. Myers sent out a continuous supply of gluten-free items to sample.

Some are naturally gluten-free, such as the homemade potato chips with dipping sauces, and the cedar-plank salmon. Some require simple substitutions from the regular menu, like serving the goat cheese fresh instead of breaded and pan-fried in the chevre salad.

Other items include pulled pork, Thai chicken salad and gluten-free pasta in a white-wine sauce.

“Getting the staff up-to-date has been the key to this,” Myers said. “We train and retrain, telling them how serious it can be if a gluten-intolerant person got a big, old crouton on their salad.”

But the more gluten-free orders he gets, the better he and his staff can do. “I think once you get over the initial crunch, and you really grasp things, it’s easier.” mhastings@wsjournal.com

About celiac disease

Celiac disease is most often referred to as gluten intolerance. For someone who has the disease, consumption of gluten — a protein found in wheat, barley and rye — causes damage to the small intestine.

The disease has many symptoms, and different people exhibit different symptoms and different sensitivities to gluten. Possible symptoms include diarrhea, bloating, weight loss, weakness, anemia, chronic fatigue, muscle cramps, migraine headaches, nerve problems and bone pain.

Because of the variety of symptoms, celiac disease is often confused with other diseases, and it often goes undiagnosed. But a panel of blood tests has been developed to screen for the disease.

Celiac disease is a chronic, inherited disease. A cure does not exist. Treatment consists of eating a diet free of all gluten. Because the disease causes nutrients to pass through the small intestine instead of being absorbed, the disease can lead to malnutrition if left untreated.

Gluten-free menus

Here are some area restaurants that offer gluten-free menus. The menus also are posted on their websites:

* Bonefish Grill, www.bonefishgrill.com

* Brixx Wood Fired Pizza, www.brixxpizza.com

* Carrabba’s Italian Grill, www.carrabbas.com

* Firebirds Wood Fired Grill, www.firebirdsrestaurants.com

* Jason’s Deli, www.jasonsdeli.com

* Mellow Mushroom, www.mellowmushroom.com

* New Town Bistro, www.newtownbistro.com

* Olive Garden, www.olivegarden.com

* Outback Steak House, www.outback.com

* River Birch Lodge, www.riverbirchlodge.com

* Village Tavern, www.villagetavern.com

Note that these menus typically contain warnings or qualifiers that say the restaurants do not assume responsibility for the accuracy of the menus, which typically have been prepared by an outside dietitian or other person.

Many gluten-free diners say that a gluten-free menu is no guarantee of a gluten-free meal. Several local diners mentioned instances when their “gluten-free meal” arrived with wheat croutons in the salad or wheat bread on the plate.

Adequate training and knowledge can be especially difficult in large restaurants or those in which employee turnover is high.

In short, a gluten-free meal is dependent on the understanding and communication of all parties involved, including the wait staff, kitchen staff and diners.

Grace Johnston, team leader of the local Gluten Intolerance Group, makes these suggestions for eating out on a gluten-free diet:

* Go when the restaurant isn’t busy and has time to accommodate special requests.

* Talk directly with the head chef or a manager about the need for a gluten-free meal.

* Ask lots of questions about ingredients and preparation.

Michael Hastings

©2011 Winston-Salem Journal (Winston Salem, N.C.)

Eating at a restaurant can be a challenge for anyone on a restricted diet.

But when eating the wrong food can make you sick, eating out can be become downright scary.

Getting sick from food is a real possibility for the growing number of Americans who have celiac disease.

People with celiac disease have an intolerance to gluten, a protein found in wheat, barley and rye. It is considered the most under-diagnosed disease in the country, and it may affect one out of every 133 Americans, according to the Gluten Intolerance Group of North America, a national support group.

In addition, many more people have found that they have a sensitivity to wheat and/or gluten. Others have chosen not to eat wheat or gluten for various reasons. Some say they feel better without it; others think it helps with weight loss.

In the past, eating out has been difficult for anyone on a gluten-free diet. In carb-crazy, wheat-loving America, sometimes a salad might be the only thing on the menu that doesn't use flour, bread, pasta or something else with gluten. And many times that salad comes with croutons.

Thomas Manning, a Forsyth County native who lives in North Raleigh, remembers eating out six years ago after he first found out he had celiac disease. Often, after he explained his situation, restaurant employees would become scared to serve him, worried that any mistake might make him sick. And many times when they did serve him, they'd offer nothing beyond a plain grilled chicken breast and a salad. "I got so tired of chicken breast and salad," he said.

But now restaurants are starting to listen to -- and welcome -- the increasing numbers of diners who avoid wheat and gluten.

"There are a lot more restaurants that offer gluten-free options," said Debbie Fisher of Clemmons, who also has celiac disease. "And the gluten-free menus have a lot more items on them."

When Martha Russell learned she had celiac disease in 2003, "some people didn't even know what gluten is," she said. "Chefs are so much more aware of this now. And they love the challenge of creating something different for you."

The Gluten Intolerance Group (www.gluten.net) has enrolled 1,620 restaurants in the country in its Gluten-Free Restaurant Awareness Program. In Winston-Salem, several restaurants now offer gluten-free options.

Extensive gluten-free menus are offered at such chains as Bonefish Grill, Carrabba's Italian Grill, Firebirds Wood Fired Grill, Outback Steak House and Village Tavern, and at such independent restaurants as New Town Bistro and River Birch Lodge.

Jason's Deli, a chain based in Texas with a location on Hanes Mall Boulevard, offers sandwiches on gluten-free bread. Mellow Mushroom and Brixx Wood Fired Pizza both offer gluten-free pizza.

Serving gluten-free meals is not as simple as removing or replacing the bread or pasta.

The gluten from wheat, barley and rye show up -- or rather hide -- in many ingredients.

"I'm very skeptical about any sauce or salad dressing," said Fran Fox, because those often use flour for thickening. Fox, who has been gluten-free for 25 years, said it does require asking a lot of questions at restaurants.

Another hidden ingredient is soy sauce, which usually contains wheat. Other ingredients, such as malted barley, lurk in many processed foods.

Russell and others tend to stay away from Chinese and other Asian restaurants that use soy sauce. They often feel more comfortable in Mexican and Indian restaurants that do not rely heavily on wheat.

But it's not just the ingredients. Cross-contamination poses a danger, too. Vegetables chopped on the same cutting board as a loaf of bread can contaminate someone's salad and make them sick.

Similarly, the cook who makes a salad with croutons and then makes a gluten-free salad can contaminate the gluten-free salad.

At New Town Bistro, chef Donny Smith pulls out a clean cutting board and clean utensils when someone orders a gluten-free item.

"It's not the best thing at 7 p.m. on a Saturday night, but there's no other way around it," Smith said. "It just becomes part of our job. We want to make sure people didn't use tongs to grab bread out of the oven, then use it to grab a gluten-free entree."

At Mellow Mushroom, general manager Margaret Waters said the staff changes aprons, washes hands and moves to a separate work area after receiving an order for a gluten-free pizza.

"We even have a different cart of ingredients -- toppings, the sauce, the cheese -- that we keep separate from everything else," she said. And the pizza is put on a special rack so it does not touch the same oven surfaces that the regular pizzas touch.

When someone orders a gluten-free sandwich at Jason's Deli, "only the managers are allowed to make it," said supervisor Nancy Hernandez. "We make it in the back of the restaurant. We get all of the ingredients fresh from the back. We don't use anything from the line" that might have come in contact with regular bread.

A plain piece of meat might seem like a safe choice, but not if it's grilled on the same spot as grilled bread. Chef Travis Myers of River Birch Lodge sautes meats on his gluten-free menu in clean pans instead of grilling them.

Myers cooks all of his breaded and other gluten foods in one deep fryer, dedicating a second fryer to gluten-free items. "We can do french fries and (homemade potato) chips and not worry about cross-contamination," he said.

Myers has a gluten-free menu of five appetizers, five salads, four sandwiches, eight entrees and three desserts.

In some cases, he has made an item gluten-free simply by removing the gluten ingredient. For instance, the seared tuna appetizer comes with pickled ginger but without the usual ginger sauce, which is made with soy sauce.

"Once we dove into the nuts and bolts of it, it was easy to make things gluten-free, because we make most things in-house," Myers said. >

River Birch has offered a gluten-free menu longer than most -- about six years. "Our lawyer's family is gluten-intolerant, so that's how we learned about it," he said.

"Word of mouth has really helped us. Now I'd say one out of every five tables we're getting a gluten-free order. A lot of times we'll have a whole party of gluten-free."

That was the case last Thursday when about a dozen members of the local Gluten Intolerance Group ate lunch at River Birch. Myers sent out a continuous supply of gluten-free items to sample.

Some are naturally gluten-free, such as the homemade potato chips with dipping sauces, and the cedar-plank salmon. Some require simple substitutions from the regular menu, like serving the goat cheese fresh instead of breaded and pan-fried in the chevre salad.

Other items include pulled pork, Thai chicken salad and gluten-free pasta in a white-wine sauce.

"Getting the staff up-to-date has been the key to this," Myers said. "We train and retrain, telling them how serious it can be if a gluten-intolerant person got a big, old crouton on their salad."

But the more gluten-free orders he gets, the better he and his staff can do. "I think once you get over the initial crunch, and you really grasp things, it's easier." mhastings@wsjournal.com

About celiac disease

Celiac disease is most often referred to as gluten intolerance. For someone who has the disease, consumption of gluten -- a protein found in wheat, barley and rye -- causes damage to the small intestine.

The disease has many symptoms, and different people exhibit different symptoms and different sensitivities to gluten. Possible symptoms include diarrhea, bloating, weight loss, weakness, anemia, chronic fatigue, muscle cramps, migraine headaches, nerve problems and bone pain.

Because of the variety of symptoms, celiac disease is often confused with other diseases, and it often goes undiagnosed. But a panel of blood tests has been developed to screen for the disease.

Celiac disease is a chronic, inherited disease. A cure does not exist. Treatment consists of eating a diet free of all gluten. Because the disease causes nutrients to pass through the small intestine instead of being absorbed, the disease can lead to malnutrition if left untreated.

Gluten-free menus

Here are some area restaurants that offer gluten-free menus. The menus also are posted on their websites:

* Bonefish Grill, www.bonefishgrill.com

* Brixx Wood Fired Pizza, www.brixxpizza.com

* Carrabba's Italian Grill, www.carrabbas.com

* Firebirds Wood Fired Grill, www.firebirdsrestaurants.com

* Jason's Deli, www.jasonsdeli.com

* Mellow Mushroom, www.mellowmushroom.com

* New Town Bistro, www.newtownbistro.com

* Olive Garden, www.olivegarden.com

* Outback Steak House, www.outback.com

* River Birch Lodge, www.riverbirchlodge.com

* Village Tavern, www.villagetavern.com

Note that these menus typically contain warnings or qualifiers that say the restaurants do not assume responsibility for the accuracy of the menus, which typically have been prepared by an outside dietitian or other person.

Many gluten-free diners say that a gluten-free menu is no guarantee of a gluten-free meal. Several local diners mentioned instances when their "gluten-free meal" arrived with wheat croutons in the salad or wheat bread on the plate.

Adequate training and knowledge can be especially difficult in large restaurants or those in which employee turnover is high.

In short, a gluten-free meal is dependent on the understanding and communication of all parties involved, including the wait staff, kitchen staff and diners.

Grace Johnston, team leader of the local Gluten Intolerance Group, makes these suggestions for eating out on a gluten-free diet:

* Go when the restaurant isn't busy and has time to accommodate special requests.

* Talk directly with the head chef or a manager about the need for a gluten-free meal.

* Ask lots of questions about ingredients and preparation.

Michael Hastings

©2011 Winston-Salem Journal (Winston Salem, N.C.)

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Foods That Really Make You Happy

Posted Sept 9, 2011

Bad day? Fight the blues without blowing your diet by picking foods that boost happy brain chemicals while helping you stay slim

When you’re in a funk, your first instinct isn’t to whip up a bowl of lentil soup or pour yourself a glass of milk. But compounds in these foods may help ward off depression, fight fatigue, and reduce anxiety by increasing levels of mood-boosting brain chemicals such as serotonin and dopamine. Traditional comfort foods, like those loaded with sugar, saturated fat, alcohol, and caffeine, on the other hand, can actually amplify edginess – not to mention blow your diet. To perk up without packing on the pounds, pick one of these nine healthy eats next time you’re feeling down.

Popcorn

The mood booster: Tryptophan

We hear tryptophan and we immediately think turkey – and tired. Truth is, when the amino acid is consumed with carbohydrates instead of protein, it’s more effective in aiding the body’s production of serotonin, a tranquility-inducing brain chemical. A study published in the journal Acta Psychiatrica Scandinavia found that foods containing tryptophan, like mustard greens, pumpkin seeds and bananas, offer mood-elevating effects. Tryptophan levels are often low in people suffering from depression, although researchers are unclear as to whether the relationship is a cause or a consequence of the condition. The next time you feel down, try 3 cups of air-popped popcorn for 100 calories instead of gnawing on a drumstick.

Walnuts

The mood booster: Alpha-linolenic acid

While EPA and DHA, two omega-3 fatty acids found in salmon, tuna, and fish oil supplements, have been touted to help depression sufferers beat the blues, a new study of 55,000 women published in the American Journal of Clinical Nutrition suggests that alpha-linolenic acid (ALA), an omega-3 fatty acid in plant foods like walnuts, soybeans, and flaxseed, is the real star in alleviating depression symptoms. In the 10-year study, Harvard University researchers found that the risk of depression was lower among women who consumed more ALA, a compound previously thought to have few health benefits.

Cottage Cheese

The mood booster: Tyrosine

Low-fat sources of protein, like egg whites and low-fat cottage cheese, are packed with tyrosine, an amino acid that aids the brain’s production of norepinephrine and dopamine, two chemicals that influence motivation and reaction time. Early studies showed that tyrosine could be used to alleviate symptoms of depression, as it is an essential building block for the mood-regulating brain chemicals norepinephrine, dopamine and serotonin. Enjoy half a cup for only 90 calories and stock up on 14 g of filling protein.

Sunflower Seeds

The mood booster: Selenium

A Nutritional Neuroscience review of five studies on selenium and depression linked deficiencies in the mineral to poorer mood. Another study published in the Journal of Maternal-Fetal and Neonatal Medicine suggests that selenium can help prevent postpartum depression. When 44 postpartum women received 100 mcg of selenium daily, they scored lower on a postnatal depression scale. While Brazil nuts offer the biggest dose of selenium – a half-ounce serving packs 272 mcg – sunflower seeds are a lower-calorie snack option. A quarter cup of roasted seeds in their shells has about 70 calories and delivers 30 percent of the daily recommended value of selenium, while a single Brazil nut packs around 30 calories.

Lentils

The mood booster: Folate

Skip the mac and cheese and make a hearty bowl of soup your new favorite comfort food. A study published in the Journal of Nutrition found that of the 2,682 middle-age Finnish men in the study, those whose diets contained the least folate were 67 percent more likely to suffer from depression. Research suggests that low levels of the B vitamin impair the metabolism of neurotransmitters, leaving your brain short on serotonin and dopamine. Get your folate fix with a cup of lentils, which contains 230 calories and provides 70 percent of your daily folate and 63 percent of your daily fiber.

Avocado

The mood booster: Oleic acid

Healthy fats, like those found in olive oil and avocados, don’t just keep belly fat at bay. They can also ward off a bad mood. Oleic acid, a monounsaturated omega-9 fatty acid, increases the feel-good chemical serotonin in the brain, keeping you calm. In a study published in the Archives of General Psychiatry, researchers at the University of Nivarra in Spain found that people who consumed a Mediterranean diet rich in fruits, nuts, fish and olive oil were 30 percent less likely to become depressed.

Citrus Fruit

The mood booster: Vitamin C

For only 60 calories a pop, it’s easy to get nearly 100 percent of your daily recommended vitamin C in one place. Skip your orange and you might end up feeling bitter. In a study conducted by doctors at Jewish General Hospital in Montreal and published in the journal Nutrition, researchers found that when vitamin C-deficient hospital patients were supplemented with 500 mg of vitamin C twice daily for 1 week they experienced a 34 percent reduction in mood disturbance. Even the smell of citrus can put you in a better state of mind. When participants in an Ohio State University study smelled lemons, they reported greater improvements in mood and had higher levels of norepinephrine compared with when they sniffed lavender or unscented water.

Low-Fat Milk

The mood boosters: Vitamin D, calcium, whey protein

While research has linked deficiencies in vitamin D and calcium – two essential nutrients found in milk and fortified juices – to mood disorders, like depression, seasonal affective disorder, and PMS, a lesser-studied compound in dairy products can help you keep your cool in high-stress situations. An American Journal of Clinical Nutrition study found that alpha-lactalbumin, a component of whey protein, improves cognitive performance in stress-prone individuals by increasing levels of tryptophan and serotonin in the brain.

Bananas

The mood booster: Magnesium

This portable treat makes a great 100-calorie snack when you’re craving something sweet. Bananas are a good source of magnesium, a mineral that helps the brain deal with stress and may help boost mood, too. In a study of 5,700 adults published in the Australian and New Zealand Journal of Psychiatry, researchers linked higher levels of anxiety and depression to study participants with lower magnesium intake. Bananas are also packed with potassium, which helps boost alertness, tryptophan, an amino acid that aids the body in producing mood-boosting serotonin and mood-stabilizing vitamin B6.

For more tips and tricks, visit Fitbie.com.

McClatchy-Tribune Information Services.

Bad day? Fight the blues without blowing your diet by picking foods that boost happy brain chemicals while helping you stay slim

When you're in a funk, your first instinct isn't to whip up a bowl of lentil soup or pour yourself a glass of milk. But compounds in these foods may help ward off depression, fight fatigue, and reduce anxiety by increasing levels of mood-boosting brain chemicals such as serotonin and dopamine. Traditional comfort foods, like those loaded with sugar, saturated fat, alcohol, and caffeine, on the other hand, can actually amplify edginess - not to mention blow your diet. To perk up without packing on the pounds, pick one of these nine healthy eats next time you're feeling down.

Popcorn

The mood booster: Tryptophan

We hear tryptophan and we immediately think turkey - and tired. Truth is, when the amino acid is consumed with carbohydrates instead of protein, it's more effective in aiding the body's production of serotonin, a tranquility-inducing brain chemical. A study published in the journal Acta Psychiatrica Scandinavia found that foods containing tryptophan, like mustard greens, pumpkin seeds and bananas, offer mood-elevating effects. Tryptophan levels are often low in people suffering from depression, although researchers are unclear as to whether the relationship is a cause or a consequence of the condition. The next time you feel down, try 3 cups of air-popped popcorn for 100 calories instead of gnawing on a drumstick.

Walnuts

The mood booster: Alpha-linolenic acid

While EPA and DHA, two omega-3 fatty acids found in salmon, tuna, and fish oil supplements, have been touted to help depression sufferers beat the blues, a new study of 55,000 women published in the American Journal of Clinical Nutrition suggests that alpha-linolenic acid (ALA), an omega-3 fatty acid in plant foods like walnuts, soybeans, and flaxseed, is the real star in alleviating depression symptoms. In the 10-year study, Harvard University researchers found that the risk of depression was lower among women who consumed more ALA, a compound previously thought to have few health benefits.

Cottage Cheese

The mood booster: Tyrosine

Low-fat sources of protein, like egg whites and low-fat cottage cheese, are packed with tyrosine, an amino acid that aids the brain's production of norepinephrine and dopamine, two chemicals that influence motivation and reaction time. Early studies showed that tyrosine could be used to alleviate symptoms of depression, as it is an essential building block for the mood-regulating brain chemicals norepinephrine, dopamine and serotonin. Enjoy half a cup for only 90 calories and stock up on 14 g of filling protein.

Sunflower Seeds

The mood booster: Selenium

A Nutritional Neuroscience review of five studies on selenium and depression linked deficiencies in the mineral to poorer mood. Another study published in the Journal of Maternal-Fetal and Neonatal Medicine suggests that selenium can help prevent postpartum depression. When 44 postpartum women received 100 mcg of selenium daily, they scored lower on a postnatal depression scale. While Brazil nuts offer the biggest dose of selenium - a half-ounce serving packs 272 mcg - sunflower seeds are a lower-calorie snack option. A quarter cup of roasted seeds in their shells has about 70 calories and delivers 30 percent of the daily recommended value of selenium, while a single Brazil nut packs around 30 calories.

Lentils

The mood booster: Folate

Skip the mac and cheese and make a hearty bowl of soup your new favorite comfort food. A study published in the Journal of Nutrition found that of the 2,682 middle-age Finnish men in the study, those whose diets contained the least folate were 67 percent more likely to suffer from depression. Research suggests that low levels of the B vitamin impair the metabolism of neurotransmitters, leaving your brain short on serotonin and dopamine. Get your folate fix with a cup of lentils, which contains 230 calories and provides 70 percent of your daily folate and 63 percent of your daily fiber.

Avocado

The mood booster: Oleic acid

Healthy fats, like those found in olive oil and avocados, don't just keep belly fat at bay. They can also ward off a bad mood. Oleic acid, a monounsaturated omega-9 fatty acid, increases the feel-good chemical serotonin in the brain, keeping you calm. In a study published in the Archives of General Psychiatry, researchers at the University of Nivarra in Spain found that people who consumed a Mediterranean diet rich in fruits, nuts, fish and olive oil were 30 percent less likely to become depressed.

Citrus Fruit

The mood booster: Vitamin C

For only 60 calories a pop, it's easy to get nearly 100 percent of your daily recommended vitamin C in one place. Skip your orange and you might end up feeling bitter. In a study conducted by doctors at Jewish General Hospital in Montreal and published in the journal Nutrition, researchers found that when vitamin C-deficient hospital patients were supplemented with 500 mg of vitamin C twice daily for 1 week they experienced a 34 percent reduction in mood disturbance. Even the smell of citrus can put you in a better state of mind. When participants in an Ohio State University study smelled lemons, they reported greater improvements in mood and had higher levels of norepinephrine compared with when they sniffed lavender or unscented water.

Low-Fat Milk

The mood boosters: Vitamin D, calcium, whey protein

While research has linked deficiencies in vitamin D and calcium - two essential nutrients found in milk and fortified juices - to mood disorders, like depression, seasonal affective disorder, and PMS, a lesser-studied compound in dairy products can help you keep your cool in high-stress situations. An American Journal of Clinical Nutrition study found that alpha-lactalbumin, a component of whey protein, improves cognitive performance in stress-prone individuals by increasing levels of tryptophan and serotonin in the brain.

Bananas

The mood booster: Magnesium

This portable treat makes a great 100-calorie snack when you're craving something sweet. Bananas are a good source of magnesium, a mineral that helps the brain deal with stress and may help boost mood, too. In a study of 5,700 adults published in the Australian and New Zealand Journal of Psychiatry, researchers linked higher levels of anxiety and depression to study participants with lower magnesium intake. Bananas are also packed with potassium, which helps boost alertness, tryptophan, an amino acid that aids the body in producing mood-boosting serotonin and mood-stabilizing vitamin B6.

For more tips and tricks, visit Fitbie.com.

McClatchy-Tribune Information Services.

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Quiz Your Sports Nutrition Knowledge

Posted Aug 24, 2011

Endurance athletes are obsessive about nutrition — not to lose weight but to improve performance. Those in the know follow Runner’s World editor-at-large Amby Burfoot’s Twitter feed: @exerscience. Take our quiz based on recent studies he has retweeted.

1. A study of the effects of zinc and selenium supplements in cyclists, published in the Biological Trace Elements Journal, showed what type of change in resting testosterone and lactate levels after four weeks of use?

a) No significant change

b) 14 percent increase in serum testosterone levels

c) 1.5 percent increase in plasma lactate

2. Some athletes believe quercetin, a plant-derived flavonoid, can improve endurance by reducing inflammation. A study, published in the International Journal of Sports Nutrition Exercise Metabolism, of runners who either ingested four quercetin chews or four placebo chews before exercise showed what?

a) Quercetin chewers’ bloodwork showed nearly twice the reduction of inflammation compared to placebo chewers.

b) Quercetin chewers actually had slightly higher inflammation levels.

c) No significant difference in the two groups.

3. True or false: The spice curcumin does not help treat inflammatory arthritis and tendinitis, according to researcher at the University of Nottingham in Great Britain and Ludwig-Maxmillians University in Munich, Germany.

4. The flavonol epicatechin, most commonly found in cocoa (chocolate, anyone?), was found to increase fatigue resistance and oxygen capacity in lab mice exercising on treadmills, according to a study in the Journal of Physiology. How much more did the epicatechin-fed mice improve on the treadmill compared to the placebo mice?

a) .01 percent improvement

b) 20 percent

c) 37 percent

5. Runners need to store glycogen in their muscles for endurance. In a study published in the British Journal of Nutrition, subjects who augmented their post-workout recovery meal with the supplement hydroxycitrate (HCA) saw what type of increase in glycogen synthesis into their muscles?

a) no increase

b) a twofold increase

c) a threefold increase

ANSWERS: 1: a; 2: c; 3: false (results showed that curcumin prevents the molecule interleukins from promoting inflammation); 4: b; 5: a.

To see more of The Sacramento Bee, or to subscribe to the newspaper, go to http://www.sacbee.com/.

Copyright © 2011, The Sacramento Bee, Calif.

Distributed by McClatchy-Tribune Information Services.

Endurance athletes are obsessive about nutrition -- not to lose weight but to improve performance. Those in the know follow Runner's World editor-at-large Amby Burfoot's Twitter feed: @exerscience. Take our quiz based on recent studies he has retweeted.

1. A study of the effects of zinc and selenium supplements in cyclists, published in the Biological Trace Elements Journal, showed what type of change in resting testosterone and lactate levels after four weeks of use?

a) No significant change

b) 14 percent increase in serum testosterone levels

c) 1.5 percent increase in plasma lactate

2. Some athletes believe quercetin, a plant-derived flavonoid, can improve endurance by reducing inflammation. A study, published in the International Journal of Sports Nutrition Exercise Metabolism, of runners who either ingested four quercetin chews or four placebo chews before exercise showed what?

a) Quercetin chewers' bloodwork showed nearly twice the reduction of inflammation compared to placebo chewers.

b) Quercetin chewers actually had slightly higher inflammation levels.

c) No significant difference in the two groups.

3. True or false: The spice curcumin does not help treat inflammatory arthritis and tendinitis, according to researcher at the University of Nottingham in Great Britain and Ludwig-Maxmillians University in Munich, Germany.

4. The flavonol epicatechin, most commonly found in cocoa (chocolate, anyone?), was found to increase fatigue resistance and oxygen capacity in lab mice exercising on treadmills, according to a study in the Journal of Physiology. How much more did the epicatechin-fed mice improve on the treadmill compared to the placebo mice?

a) .01 percent improvement

b) 20 percent

c) 37 percent

5. Runners need to store glycogen in their muscles for endurance. In a study published in the British Journal of Nutrition, subjects who augmented their post-workout recovery meal with the supplement hydroxycitrate (HCA) saw what type of increase in glycogen synthesis into their muscles?

a) no increase

b) a twofold increase

c) a threefold increase

ANSWERS: 1: a; 2: c; 3: false (results showed that curcumin prevents the molecule interleukins from promoting inflammation); 4: b; 5: a.

To see more of The Sacramento Bee, or to subscribe to the newspaper, go to http://www.sacbee.com/.

Copyright © 2011, The Sacramento Bee, Calif.

Distributed by McClatchy-Tribune Information Services.

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Sleep Helps Boost Athletic Performance

Posted Aug 6, 2011

San Francisco — In a sleep-deprived country, where most Americans struggle just to get eight hours of shut-eye a night, a Stanford researcher asked a rather outlandish question: What would happen if folks aimed for 10 hours of sleep?

The answer for a basketball player: a better free-throw shot.

That’s according to a study, published in this month’s edition of the journal Sleep, of 11 players from Stanford’s varsity basketball team. They tried to get at least 10 hours of sleep every night for five to seven weeks — or two to three hours more than they were used to.

The players didn’t quite make it to 10 hours, but they did add about 90 minutes of sleep time, and the results were noticeable.

Collectively, they took almost a full second off of their times in 282-foot sprints on a basketball court, and they improved the accuracy of both their free-throw and three-point shooting by 9 percent.

“What these findings suggest is that these athletes were operating at a sub-optimal level. They’d accumulated a sleep debt,” said Cheri Mah , a researcher at the Stanford Sleep Disorders Clinic and lead author of the study. “It’s not that they couldn’t function — they were doing fine — but that they might not have been at their full potential.”

The study was very small, and the results will need to be confirmed with a larger group of athletes, Mah said. But the fact that every one of the 11 players saw improvements is pretty strong evidence that extra sleep can elevate athletic performance.

Whether the results would apply to the general population — in better performance at work or more energy at the gym — is hard to say, sleep experts say. But it’s been well documented that sleep deprivation negatively effects people’s short-term memory and moods, so it stands to reason that more sleep could have positive effects.

“The issue of athletic performance probably doesn’t apply to everyone. But everyone probably underestimates the impact of sleep deprivation,” said Dr. David Claman , director of the University of California at San Francisco Sleep Disorders Center.

In the Stanford study, the athletes first recorded their normal sleep schedule for four weeks, and on average they reported close to eight hours of sleep on a typical night. They all said they were already in peak physical condition.

Next, the athletes spent five to seven weeks trying to get much more sleep than usual, and they estimated they got on average about 10 1/2 hours of sleep every night. Their athletic improvements, they told researchers, were startling.

Aside from the improved shooting and running, they performed better on reaction tests, were less fatigued throughout the day, and their overall mood picked up.

It’s worth noting that the players probably didn’t get as much sleep as they thought. All of them wore a device on their wrist that measured their sleep time by monitoring their movements.

According to the devices, the players averaged about 6 hours and 45 minutes of sleep during the first four weeks of the study, and 8 1/2 hours during the next five to seven weeks.

Sleep experts warned that it might not be a good idea for everyone to aim for 10 hours of sleep every night. Aside from the fact that it can be impractical — Americans seem to have a tough enough time getting just eight hours — there’s a “U-shaped curve” for sleep duration.

In other words, too much sleep can be just about as bad for overall health as too little, research has shown. That’s why most people should aim for seven to nine hours, said Dr. Anil Rama , medical director of the Sleep Medicine Laboratory at Kaiser San Jose.

Still, the Stanford study seems to demonstrate that athletes — elite or not — might seriously consider making sleep a part of their training programs, alongside nutrition or weight lifting, sleep experts said.

Scott Dunlap , an elite-level distance runner who is training for this month’s San Francisco Marathon, said he started incorporating sleep into his training a year or two ago.

“If you look at my training plan, sleep is right there along with mileage and pace,” said Dunlap, 42, who typically gets about six or seven hours of sleep during a regular training cycle, but bumps that up to nine or 10 hours in the two weeks before a big race.

“Once I started tracking my sleep, I realized I wasn’t getting nearly enough,” he said. “My performance picked up dramatically when I slept more. It was the difference between finishing barely in the top 10 and finishing on the podium.”

San Francisco -- In a sleep-deprived country, where most Americans struggle just to get eight hours of shut-eye a night, a Stanford researcher asked a rather outlandish question: What would happen if folks aimed for 10 hours of sleep?

The answer for a basketball player: a better free-throw shot.

That's according to a study, published in this month's edition of the journal Sleep, of 11 players from Stanford's varsity basketball team. They tried to get at least 10 hours of sleep every night for five to seven weeks -- or two to three hours more than they were used to.

The players didn't quite make it to 10 hours, but they did add about 90 minutes of sleep time, and the results were noticeable.

Collectively, they took almost a full second off of their times in 282-foot sprints on a basketball court, and they improved the accuracy of both their free-throw and three-point shooting by 9 percent.

"What these findings suggest is that these athletes were operating at a sub-optimal level. They'd accumulated a sleep debt," said Cheri Mah , a researcher at the Stanford Sleep Disorders Clinic and lead author of the study. "It's not that they couldn't function -- they were doing fine -- but that they might not have been at their full potential."

The study was very small, and the results will need to be confirmed with a larger group of athletes, Mah said. But the fact that every one of the 11 players saw improvements is pretty strong evidence that extra sleep can elevate athletic performance.

Whether the results would apply to the general population -- in better performance at work or more energy at the gym -- is hard to say, sleep experts say. But it's been well documented that sleep deprivation negatively effects people's short-term memory and moods, so it stands to reason that more sleep could have positive effects.

"The issue of athletic performance probably doesn't apply to everyone. But everyone probably underestimates the impact of sleep deprivation," said Dr. David Claman , director of the University of California at San Francisco Sleep Disorders Center.

In the Stanford study, the athletes first recorded their normal sleep schedule for four weeks, and on average they reported close to eight hours of sleep on a typical night. They all said they were already in peak physical condition.

Next, the athletes spent five to seven weeks trying to get much more sleep than usual, and they estimated they got on average about 10 1/2 hours of sleep every night. Their athletic improvements, they told researchers, were startling.

Aside from the improved shooting and running, they performed better on reaction tests, were less fatigued throughout the day, and their overall mood picked up.

It's worth noting that the players probably didn't get as much sleep as they thought. All of them wore a device on their wrist that measured their sleep time by monitoring their movements.

According to the devices, the players averaged about 6 hours and 45 minutes of sleep during the first four weeks of the study, and 8 1/2 hours during the next five to seven weeks.

Sleep experts warned that it might not be a good idea for everyone to aim for 10 hours of sleep every night. Aside from the fact that it can be impractical -- Americans seem to have a tough enough time getting just eight hours -- there's a "U-shaped curve" for sleep duration.

In other words, too much sleep can be just about as bad for overall health as too little, research has shown. That's why most people should aim for seven to nine hours, said Dr. Anil Rama , medical director of the Sleep Medicine Laboratory at Kaiser San Jose.

Still, the Stanford study seems to demonstrate that athletes -- elite or not -- might seriously consider making sleep a part of their training programs, alongside nutrition or weight lifting, sleep experts said.

Scott Dunlap , an elite-level distance runner who is training for this month's San Francisco Marathon, said he started incorporating sleep into his training a year or two ago.

"If you look at my training plan, sleep is right there along with mileage and pace," said Dunlap, 42, who typically gets about six or seven hours of sleep during a regular training cycle, but bumps that up to nine or 10 hours in the two weeks before a big race.

"Once I started tracking my sleep, I realized I wasn't getting nearly enough," he said. "My performance picked up dramatically when I slept more. It was the difference between finishing barely in the top 10 and finishing on the podium."

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Children Who Survive Cancer Face Higher Risk of Future Cancer

Posted July 4, 2011

In another study underscoring the daunting risks facing survivors of childhood cancer, scientists at St. Jude Children’s Research Hospital report that about 1 in 10 of the survivors will go on to fight second tumors and many will develop third and fourth cancers.

The study, published Monday in the Journal of Clinical Oncology, is the first to enumerate the risks facing adults who survived cancer as children.

It highlights the need for vigilant screening of the survivors, said Dr. Greg Armstrong, an assistant member at St. Jude’s department of epidemiology and cancer control and the principal investigator on the study.

“It’s hard to know what the future holds for this group, but it is concerning,” Armstrong said.

As long-term, overall survival rates for childhood cancer have soared to 80 percent because of research at St. Jude and elsewhere, scientists have shown heightened interest in the myriad health issues confronting the growing population of survivors.

Their primary tool has been the Childhood Cancer Survivor Study, a federally funded project for which St. Jude is the coordinating institution. The 14,358 survivors enrolled in it had been diagnosed between 1970 and 1986, when they were 20 or younger.

The findings reported Monday are from the latest of 170 studies generated by the survivor project. Last year, Armstrong and other researchers reported that survivors of childhood cancer who contract either basal or squamous-cell skin cancer face an almost one-in-five chance of developing a more aggressive type of tumor within 15 years.

The latest study showed that 1,382, or 9.6 percent of the individuals in the survivor project, developed new tumors unrelated to their original cancers. Of that group, 386, or about 30 percent, developed third tumors, while 153 had four or more.

“Now that these childhood-cancer survivors are aging, we’re seeing that they are at extremely high risk for a third and fourth cancer,” Armstrong said.

The median age of the survivor group was 32, well before the stage in life when rates of prostate, breast and other cancers surge in the general population.

The reasons for the elevated risks likely include the radiation therapy that 70 percent of the survivors’ group underwent, Armstrong said. More recent treatment methods rely less on heavy radiation.

But other factors play a role as well, he said. For one thing, survivors afflicted with multiple cancers might be genetically predisposed to the disease, or particularly vulnerable to the effects of radiation.

Armstrong said the study makes all too clear the need for survivors to get frequent cancer screenings. For instance, women who received chest radiation to fight childhood tumors should begin getting regular mammograms by age 25 — 15 years before those in the general population generally start receiving them.

Additional cancers aren’t the only threats facing survivors of childhood tumors. Another recent study led by St. Jude investigators showed that sleep and fatigue problems can sharply reduce the cognitive abilities of survivors.

“The difficulty with the cancer survivors is they’re already at risk for neuro-cognitive problems because they’ve had radiation to the brain and chemotherapy,” said Kevin Krull, an associate member of the department of epidemiology and cancer control at St. Jude and the study’s corresponding author. “When you add sleep difficulties on top of that, it significantly exacerbates the problem.”

Tom Charlier: (901) 529-2572

To see more of The Commercial Appeal or to subscribe to the newspaper, go to http://www.commercialappeal.com.

Copyright © 2011, The Commercial Appeal, Memphis, Tenn.

Distributed by McClatchy-Tribune Information Services.

In another study underscoring the daunting risks facing survivors of childhood cancer, scientists at St. Jude Children's Research Hospital report that about 1 in 10 of the survivors will go on to fight second tumors and many will develop third and fourth cancers.

The study, published Monday in the Journal of Clinical Oncology, is the first to enumerate the risks facing adults who survived cancer as children.

It highlights the need for vigilant screening of the survivors, said Dr. Greg Armstrong, an assistant member at St. Jude's department of epidemiology and cancer control and the principal investigator on the study.

"It's hard to know what the future holds for this group, but it is concerning," Armstrong said.

As long-term, overall survival rates for childhood cancer have soared to 80 percent because of research at St. Jude and elsewhere, scientists have shown heightened interest in the myriad health issues confronting the growing population of survivors.

Their primary tool has been the Childhood Cancer Survivor Study, a federally funded project for which St. Jude is the coordinating institution. The 14,358 survivors enrolled in it had been diagnosed between 1970 and 1986, when they were 20 or younger.

The findings reported Monday are from the latest of 170 studies generated by the survivor project. Last year, Armstrong and other researchers reported that survivors of childhood cancer who contract either basal or squamous-cell skin cancer face an almost one-in-five chance of developing a more aggressive type of tumor within 15 years.

The latest study showed that 1,382, or 9.6 percent of the individuals in the survivor project, developed new tumors unrelated to their original cancers. Of that group, 386, or about 30 percent, developed third tumors, while 153 had four or more.

"Now that these childhood-cancer survivors are aging, we're seeing that they are at extremely high risk for a third and fourth cancer," Armstrong said.

The median age of the survivor group was 32, well before the stage in life when rates of prostate, breast and other cancers surge in the general population.

The reasons for the elevated risks likely include the radiation therapy that 70 percent of the survivors' group underwent, Armstrong said. More recent treatment methods rely less on heavy radiation.

But other factors play a role as well, he said. For one thing, survivors afflicted with multiple cancers might be genetically predisposed to the disease, or particularly vulnerable to the effects of radiation.

Armstrong said the study makes all too clear the need for survivors to get frequent cancer screenings. For instance, women who received chest radiation to fight childhood tumors should begin getting regular mammograms by age 25 -- 15 years before those in the general population generally start receiving them.

Additional cancers aren't the only threats facing survivors of childhood tumors. Another recent study led by St. Jude investigators showed that sleep and fatigue problems can sharply reduce the cognitive abilities of survivors.

"The difficulty with the cancer survivors is they're already at risk for neuro-cognitive problems because they've had radiation to the brain and chemotherapy," said Kevin Krull, an associate member of the department of epidemiology and cancer control at St. Jude and the study's corresponding author. "When you add sleep difficulties on top of that, it significantly exacerbates the problem."

Tom Charlier: (901) 529-2572

To see more of The Commercial Appeal or to subscribe to the newspaper, go to http://www.commercialappeal.com.

Copyright © 2011, The Commercial Appeal, Memphis, Tenn.

Distributed by McClatchy-Tribune Information Services.

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Runners Need to Know Their Carbs

Posted April 30, 2011

Frankfurt (dpa) – The legs are heavy, the heartbeat rapid, the fatigue total. Many long-distance runners have experienced this state. Some then immediately ingest large amounts of glucose. Others say this only makes the fatigue worse.

In his bestselling book “Ultra-marathon Man: Confessions of an All-Night Runner,” American running guru Dean Karnazes writes that he has completely eliminated refined sugar from his diet. Is sugar really so bad? It is a main ingredient, after all, in many energy drinks.

Sugar is a member of the carbohydrate family. Carbohydrates are found in foods are varied as whole-grain bread and vegetables, and enter the bloodstream at different speeds. “Slow” carbohydrates deliver energy longer, while “fast” carbohydrates give an immediate energy boost.

The glycemic index (GI) is a scale that measures how a food’s carbohydrates affect blood sugar levels, noted Thomas Konrad, director of the Institute of Metabolic Research (ISF) in Frankfurt.

High GI carbohydrates such as white bread and sweets cause blood sugar levels to rise very rapidly, Konrad explained. This prompts the body to release the hormone insulin. But is that bad?

“Insulin channels excess sugar from the blood into energy storage,” remarked German running coach and author Herbert Steffny, who was a professional marathon runner for many years. This is good during a run, he said, because muscles are supplied with fuel and carbohydrate reserves are built up.

“But you don’t burn calories when you snack in front of the television set,” he said. “Then the insulin works like a fattening hormone.” So when does a runner need sugar?

“Someone who likes to push it to the limit sometimes, runs for over an hour or is training for a moderate city run needs a quick source of energy during long training sessions,” said Hans Braun, a nutritionist at the German Sport University in Cologne. Such sources are primarily energy drinks, bars and gels, which contain a lot of sugar.

The question for leisure-time runners, though, is how strenuous must a training regimen be before “fast” carbohydrates are really necessary.

“You don’t need them at all either before or during a normal endurance run of up to an hour,” Steffny said. So leisure-time athletes with no ambitions to run a marathon should ban “fast” carbohydrates from their diet.

After training, too, it is a good idea to fill up the body’s energy stores with “slow” carbohydrates, Steffny said. They are found in foods including potatoes, vegetables, whole-grain bread and oat flakes. Sugar, on the other hand, is a fattener whether you are a runner or not. As a rule, it is unnecessary for most runners’ “normal” training runs.

The body requires a quick energy boost only during long training sessions or competition. Karnazes is a case in point. In his book, he lists the foods he ate during a 199-mile run, which included five chocolate cookies, four peanut butter sandwiches and a cheesecake.

In Braun’s view, it is sufficient for leisure-time runners when about half of their energy comes from carbohydrates.

“Someone training for a race definitely needs more, though,” noted Steffny, who also recommends high-quality protein after training. “You don’t need powder for that. Low-fat curd cheese, eggs and fish are cheaper,” he said, adding that about a quarter of the calories should come from high-quality oils and fats.

Frankfurt (dpa) - The legs are heavy, the heartbeat rapid, the fatigue total. Many long-distance runners have experienced this state. Some then immediately ingest large amounts of glucose. Others say this only makes the fatigue worse.

In his bestselling book "Ultra-marathon Man: Confessions of an All-Night Runner," American running guru Dean Karnazes writes that he has completely eliminated refined sugar from his diet. Is sugar really so bad? It is a main ingredient, after all, in many energy drinks.

Sugar is a member of the carbohydrate family. Carbohydrates are found in foods are varied as whole-grain bread and vegetables, and enter the bloodstream at different speeds. "Slow" carbohydrates deliver energy longer, while "fast" carbohydrates give an immediate energy boost.

The glycemic index (GI) is a scale that measures how a food's carbohydrates affect blood sugar levels, noted Thomas Konrad, director of the Institute of Metabolic Research (ISF) in Frankfurt.

High GI carbohydrates such as white bread and sweets cause blood sugar levels to rise very rapidly, Konrad explained. This prompts the body to release the hormone insulin. But is that bad?

"Insulin channels excess sugar from the blood into energy storage," remarked German running coach and author Herbert Steffny, who was a professional marathon runner for many years. This is good during a run, he said, because muscles are supplied with fuel and carbohydrate reserves are built up.

"But you don't burn calories when you snack in front of the television set," he said. "Then the insulin works like a fattening hormone." So when does a runner need sugar?

"Someone who likes to push it to the limit sometimes, runs for over an hour or is training for a moderate city run needs a quick source of energy during long training sessions," said Hans Braun, a nutritionist at the German Sport University in Cologne. Such sources are primarily energy drinks, bars and gels, which contain a lot of sugar.

The question for leisure-time runners, though, is how strenuous must a training regimen be before "fast" carbohydrates are really necessary.

"You don't need them at all either before or during a normal endurance run of up to an hour," Steffny said. So leisure-time athletes with no ambitions to run a marathon should ban "fast" carbohydrates from their diet.

After training, too, it is a good idea to fill up the body's energy stores with "slow" carbohydrates, Steffny said. They are found in foods including potatoes, vegetables, whole-grain bread and oat flakes. Sugar, on the other hand, is a fattener whether you are a runner or not. As a rule, it is unnecessary for most runners' "normal" training runs.

The body requires a quick energy boost only during long training sessions or competition. Karnazes is a case in point. In his book, he lists the foods he ate during a 199-mile run, which included five chocolate cookies, four peanut butter sandwiches and a cheesecake.

In Braun's view, it is sufficient for leisure-time runners when about half of their energy comes from carbohydrates.

"Someone training for a race definitely needs more, though," noted Steffny, who also recommends high-quality protein after training. "You don't need powder for that. Low-fat curd cheese, eggs and fish are cheaper," he said, adding that about a quarter of the calories should come from high-quality oils and fats.

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How to Sleep Your Way to a Healthy Weight

Whether you occasionally have a tough time falling asleep or you just can't seem to stay asleep at times, too many nights spent lying awake can catch up with you faster than you may think. And research is now showing that your waistline could be the first place you notice it - with imbalances in your blood sugar and your heart health not far behind.

What's behind this dangerous domino effect? Well, without enough quality sleep, your body's natural restorative cycles are disrupted, along with its levels of several key regulatory hormones-namely leptin, ghrelin, adiponectin and melatonin. While leptin and ghrelin influence your appetite by telling your body when to stop and start eating, adiponectin is essential for normal weight, blood sugar and cholesterol control.

Research indicates that melatonin plays a similar role, responsible for maintaining both a healthy weight and a healthy lipid profile-not to mention proper glucose metabolism. The bottom line: Cut back on your sleep, and you could be setting your body up for metabolic imbalance.

It's clear that getting quality sleep every night should be one of your top priorities-especially if you're overweight. But if you find that occasional sleepless nights are occurring despite even your best efforts to wind down, a little help may be in order to get the shuteye you need.

Nightly melatonin supplementation is a good place to start, with research indicating that it can promote more restful sleep while helping you to keep healthy weight and cholesterol levels. Along with melatonin, you can also turn to a few time-tested and research-supported botanicals to ensure a good night's sleep: Studies show that a blend of Magnolia officinalis bark and Ziziphus spinosa seed extracts (also known as Seditol) may bind with sleep-promoting receptors to enhance relaxation and fight fatigue at the same time.

Hops also contains powerful natural sleep-promoting compounds, while lemon balm has been shown to aid occasional sleeplessness - at the same time improving your mood, stress responses and cognitive performance, too. Similarly, clinical study indicates that valerian is able to calm nerves and enhance sleep quality-along with passion flower, which is another safe and effective solution for better quality sleep. You'll find all of these botanicals combined in Vitamin Research Products nightly formula Herbal Sleep.

Getting your sleep schedule back on track is half the battle when it comes to weight gain, but you can also help your body along with a blend of acacia gum polysaccharides and esterified fatty acids. Clinical trials show that this combo (called LeptinX, also available from VRP) can help balance serum leptin, adiponectin and insulin levels while assisting in the management of both weight and body fat measures-making it a safe and effective natural solution for those sometimes sleep-starved scale watchers.



References:
1. Knutson KL, Van Cauter E. Associations between sleep loss and increased risk of obesity and diabetes. Ann N Y Acad Sci. 2008;1129:287-304.
2. Shankar A, Syamala S, Kalidindi S. Insufficient rest or sleep and its relation to cardiovascular disease, diabetes and obesity in a national, multiethnic sample. PLoS One. 2010 Nov 30;5(11):e14189.
3. Broussard J, Brady MJ. The impact of sleep disturbances on adipocyte function and lipid metabolism. Best Pract Res Clin Endocrinol Metab. 2010 Oct;24(5):763-73.
4. American Sleep Apnea Association website, www.sleepapnea.org, accessed January 5, 2011.
5. Morselli L, Leproult R, Balbo M, Spiegel K. Role of sleep duration in the regulation of glucose metabolism and appetite. Best Pract Res Clin Endocrinol Metab. 2010 Oct;24(5):687-702.
6. Spiegel K, Tasali E, Penev P, Van Cauter E. Brief communication: sleep curtailment in healthy young men is associated with decreased leptin levels, elevated ghrelin levels, and increased hunger and appetite. Annals of Internal Medicine. 2004;141(11):846-850.
7. Nakagawa Y, Kishida K, Kihara S, Yoshida R, Funahashi T, Shimomura I. Nocturnal Falls of Adiponectin Levels in Sleep Apnea with Abdominal Obesity and Impact of Hypoxia-Induced Dysregulated Adiponectin Production in Obese Murine Mesenteric Adipose Tissue. J Atheroscler Thromb. 2010 Dec 1. Published Online Ahead of Print.
8. Vasseur F. Adiponectin and its receptors: partners contributing to the "vicious circle"leading to the metabolic syndrome? Pharmacol Res. 2006 Jun;53(6):478-81.
9. Ukkola O, Santaniemi M. Adiponectin: a link between excess adiposity and associated comorbidities? J Mol Med. 2002 Nov;80(11):696-702.
10. Renaldi O, Pramono B, Sinorita H, Purnomo LB, Asdie RH, Asdie AH. Hypoadiponectinemia: a risk factor for metabolic syndrome. Acta Med Indones. 2009 Jan;41(1):20-4.
11. Agil A, Navarro-Alarcà n M, Ruiz R, Abuhamadah S, El-Mir MY, Và zquez GF. Beneficial effects of melatonin on obesity and lipid profile in young Zucker diabetic fatty rats. J Pineal Res. 2010 Nov 19. Published Online Ahead of Print.
12. Contreras-Alcantara S, Baba K, Tosini G. Removal of melatonin receptor type 1 induces insulin resistance in the mouse. Obesity (Silver Spring). 2010 Sep;18(9):1861-3.
13. Olde Rikkert MG, Rigaud AS. Melatonin in elderly patients with insomnia. A systematic review. Z Gerontol Geriatr. 2001 Dec;34(6):491-7.
14. Nunes DM, Mota RM, Machado MO, Pereira ED, Bruin VM, Bruin PF. Effect of melatonin administration on subjective sleep quality in chronic obstructive pulmonary disease. Braz J Med Biol Res. 2008 Oct;41(10):926-31.
15. Bourne RS, Mills GH, Minelli C. Melatonin therapy to improve nocturnal sleep in critically ill patients: encouraging results from a small randomised controlled trial. Crit Care. 2008;12(2):R52.
16. Koetter U, Barrett M, Lacher S, Abdelrahman A, Dolnick D. Interactions of Magnolia and Ziziphus Extracts with Selected Central Nervous System Receptors. J Ethnopharmacol. 2009 Jul 30;124(3):421-5.
17. LaValle J, Pelletier M, LaValle L, Barrett M, Koetter U, Dolnick D. A Proprietary Blend of Magnolia and Ziziphus Extracts Assists with Sleep: An Open-Label Assessment. Unpublished study.
18. Wohlfart R, HÃ nsel R, Schmidt H. The Sedative-hypnotic Principle of Hops. Planta Med. 1983 Jun;48(6):120-3.
19. Soulimani R, et al. Neurotropic action of the hydroalcoholic extract of Melissa officinalis in the mouse. Planta Med. 1991;57:105-109.
20. Kennedy DO, Little W, Scholey AB. Attenuation of laboratory-induced stress in humans after acute administration of Melissa officinalis (Lemon Balm). Psychosom Med. 2004 Jul-Aug;66(4):607-13.
21. Houghton PJ. The scientific basis for the reputed activity of Valerian. J Pharm Pharmacol. 1999;51:505-12.
22. Leathwood PD, Chauffard F, Heck E, Munoz-Box R. Aqueous extract of valerian root (Valeriana officinalis L.) improves sleep quality in man. Pharmacol Biochem Behav. 1982;17:65-71.
23. Jellin JM, Gregory PJ, Batz F, Hitchens K, et al. Pharmacist's Letter/Prescriber's Letter Natural Medicines Comprehensive Database. 5ht ed. Stockton CA. Therapeutic Research Faculty. 2003. p1014.
24. Fragala MS, Kraemer WJ, Volek JS, et al. Influences of a dietary supplement in combination with an exercise and diet regimen on adipocytokines and adiposity in women who are overweight. Eur J Appl Physiol. 2009;105:665-72.

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Manage Your Spring Fever

Posted April 10, 2011

BERLIN — The weather is getting warmer and the days longer, the first buds are sprouting and birds are back to chirping in the morning. Not everyone enjoys spring, though. Some people suffer from spring fever, whose symptoms include circulatory problems, lethargy and tiredness. For them, the switch to summer time in late March is especially upsetting.

But there are two pieces of good news for those who lack a spring in their step when winter wanes. First, there are ways for people to recharge their batteries. Second, spring fever symptoms disappear no later than the end of April.

“By May, a balance has been reestablished,” said Thomas Weiss, a general practitioner and psychotherapist in the German city of Mannheim.

Spring fever is a sign that the body is acclimating to the new conditions, namely more ultraviolet (UV) radiation and warmth. Ill and elderly people have the greatest problems in adapting. And more women are affected than men, Weiss said.

The increased sunlight upsets the body’s hormonal balance. “More serotonin is produced because of the UV rays,” explained Michael Schellberg, a psychologist in Hamburg.

Serotonin is known as the “happiness hormone.” But it takes a while until serotonin has gained the upper hand over the hormone melatonin, which causes drowsiness. The body produces melatonin in greater amounts in the dark months of winter. The “struggle” between serotonin and melatonin exhausts the body.

Blood vessels also adjust to the warm season by expanding. Blood pressure drops and people become tired.

“A lot of bacteria become active at spring temperatures,” remarked Schellberg, noting another possible cause of fatigue. People often do not notice that they have an infection. Their bodies defend themselves without clear signs of illness, but they feel run-down.

The time switch in late March makes springtime even more difficult for sensitive people. Losing an hour can knock them off their stride for days or even weeks because every healthy person has a biological clock.

“It’s situated on the lower floor of the brain — in the hypothalamus, to be precise,” said Horst-Werner Korf, director of the Senckenberg Chronomedical Institute in Frankfurt. The hypothalamus is the seat of the autonomic nervous system — also known as the vegetative nervous system — and is responsible for such things as maintaining blood pressure, controlling body weight and appetite, and regulating sleep and arousal.

People are not at the mercy of the body’s adaptive inadequacies, however. To fight spring fatigue, Weiss recommends exercise, contrast showers, sauna sessions and stepping outside briefly without a jacket now and then during the cool months, for example to go to the mailbox.

“This boosts the body’s adaptability,” he said, adding that no-one would catch a cold from such a short outing into the cold. As regards saunas, he said it did not matter how hot they were. “What’s important is that cold comes afterwards,” he said. Taking a lukewarm shower after a sauna session has no beneficial effect.

The mind also plays an important role in spring fever, so having the right attitude helps.

“Some people don’t really feel up to spring with all its activities,” Schellberg said. They have made themselves comfortable during the winter months, perhaps with food high in calories. In spring, life becomes lively again. Though it is time to get off the sofa, some people prefer to prolong their winter hibernation and find an excuse for it in spring fever.

There is no problem with that. After all, experts say, by May at the latest everyone has overcome the seasonal lethargy.

“Then, like it or not, people start feeling frisky,” Schellberg remarked. But until then, he said, outdoor exercise and light meals can ease the transition.

To see more of dpa, go to http://www.dpa.de/English.82.0.html

Copyright © 2011, dpa, Berlin

BERLIN -- The weather is getting warmer and the days longer, the first buds are sprouting and birds are back to chirping in the morning. Not everyone enjoys spring, though. Some people suffer from spring fever, whose symptoms include circulatory problems, lethargy and tiredness. For them, the switch to summer time in late March is especially upsetting.

But there are two pieces of good news for those who lack a spring in their step when winter wanes. First, there are ways for people to recharge their batteries. Second, spring fever symptoms disappear no later than the end of April.

"By May, a balance has been reestablished," said Thomas Weiss, a general practitioner and psychotherapist in the German city of Mannheim.

Spring fever is a sign that the body is acclimating to the new conditions, namely more ultraviolet (UV) radiation and warmth. Ill and elderly people have the greatest problems in adapting. And more women are affected than men, Weiss said.

The increased sunlight upsets the body's hormonal balance. "More serotonin is produced because of the UV rays," explained Michael Schellberg, a psychologist in Hamburg.

Serotonin is known as the "happiness hormone." But it takes a while until serotonin has gained the upper hand over the hormone melatonin, which causes drowsiness. The body produces melatonin in greater amounts in the dark months of winter. The "struggle" between serotonin and melatonin exhausts the body.

Blood vessels also adjust to the warm season by expanding. Blood pressure drops and people become tired.

"A lot of bacteria become active at spring temperatures," remarked Schellberg, noting another possible cause of fatigue. People often do not notice that they have an infection. Their bodies defend themselves without clear signs of illness, but they feel run-down.

The time switch in late March makes springtime even more difficult for sensitive people. Losing an hour can knock them off their stride for days or even weeks because every healthy person has a biological clock.

"It's situated on the lower floor of the brain -- in the hypothalamus, to be precise," said Horst-Werner Korf, director of the Senckenberg Chronomedical Institute in Frankfurt. The hypothalamus is the seat of the autonomic nervous system -- also known as the vegetative nervous system -- and is responsible for such things as maintaining blood pressure, controlling body weight and appetite, and regulating sleep and arousal.

People are not at the mercy of the body's adaptive inadequacies, however. To fight spring fatigue, Weiss recommends exercise, contrast showers, sauna sessions and stepping outside briefly without a jacket now and then during the cool months, for example to go to the mailbox.

"This boosts the body's adaptability," he said, adding that no-one would catch a cold from such a short outing into the cold. As regards saunas, he said it did not matter how hot they were. "What's important is that cold comes afterwards," he said. Taking a lukewarm shower after a sauna session has no beneficial effect.

The mind also plays an important role in spring fever, so having the right attitude helps.

"Some people don't really feel up to spring with all its activities," Schellberg said. They have made themselves comfortable during the winter months, perhaps with food high in calories. In spring, life becomes lively again. Though it is time to get off the sofa, some people prefer to prolong their winter hibernation and find an excuse for it in spring fever.

There is no problem with that. After all, experts say, by May at the latest everyone has overcome the seasonal lethargy.

"Then, like it or not, people start feeling frisky," Schellberg remarked. But until then, he said, outdoor exercise and light meals can ease the transition.

To see more of dpa, go to http://www.dpa.de/English.82.0.html

Copyright © 2011, dpa, Berlin

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The Science of a Hangover

Posted Jan 22, 2011

Sometimes the old methods may work best.

Researchers at Thomas Jefferson University say that they’ve identified a key agent in the brain chemistry responsible for hangover headaches and that a good remedy is one tried by every tormented soul who’s ever groped for a morning-after cup of coffee:

Caffeine.

The stimulant has long been an ingredient in over-the-counter headache medications. But the Jefferson study is the first to link caffeine’s effectiveness to its ability to block the activity of a chemical called adenosine.

The researchers, who conducted their study on laboratory rats, also found they could relieve alcohol-induced headaches with an anti-inflammatory drug in the same family as ibuprofen. (And yes, there is a way to tell if a rodent feels like your Uncle Ed after a bender. More on that later.)

While the research left some other scientists unconvinced, it represented a foray into an area of medicine that doesn’t get much study. That may be because hangovers elicit little sympathy, said alcoholism researcher Robert Swift, a professor of psychiatry and human behavior at Brown University’s Alpert Medical School.

“There are people who feel that one deserves to get a hangover, a negative consequence of drinking that might deter further drinking,” he said.

Deserved or not, the affliction has stricken mankind at least since biblical times, as another researcher noted a few years ago in the Annals of Internal Medicine. See Isaiah 5:11, which says, “Woe unto them that rise up early in the morning, that they may follow strong drink.”

The new study was overseen by Michael L. Oshinsky, director of preclinical research at the Jefferson Headache Center.

In the journal PLoS One, he and colleagues wrote that they began by giving an “inflammatory soup” to the rats — administered through a small hole in the skull, multiple times over a three-week period, to make them more sensitive. Such rats have previously been shown to be extra-sensitive to some of the same chemicals that trigger migraines in humans.

The researchers then gave the animals the equivalent of one alcoholic drink, and they proceeded to block various steps in the pathway of metabolizing alcohol, so as to see which by-products led to headache-like symptoms.

They concluded that the problem starts with a chemical called acetate. Excess acetate leads in turn to the formation of adenosine, which accumulates in the brain and appears to be a chief culprit in headaches, the authors wrote.

The presence or absence of “headaches” in the animals was determined by prodding them with nylon filaments around the eye area, the same area that becomes tender in some human migraine suffers. A rat that responded by recoiling or stroking its face was deemed to have “hangover-like hypersensitivity.” Rats that got caffeine or the anti-inflammatory drug, on the other hand, showed no such reaction.

In a search of the literature, Oshinsky found another intriguing clue. Dialysis clinics used to administer acetate to kidney patients, and 25 percent of them would report getting headaches.

“That was the real instant for me to say, ‘Oh, it’s the acetate,’ ” he said.

Swift, the Brown University professor, said the researchers’ use of the rat model was “reasonable” and said the breakdown of acetate may indeed contribute to headaches. But he cautioned that a hangover can include plenty of other symptoms, such as nausea, fatigue, and aversion to bright light.

“I don’t think we have a definitive answer about what causes hangover,” he said. “Nor do we have a definitive cure.”

Another source of hangover malaise, Swift said, may be that alcohol causes the liver to release hormones called inflammatory cytokines — the same chemicals that play a role in making a flu patient feel lousy.

The caffeine finding did not surprise one local observer of alcohol consumption: Michele Eyre, a bartender at Archie’s in Jenkintown.

“That does help,” she confirmed, when told of the research at Jefferson.

The morning after a night of excess, Eyre said, bleary-eyed patrons have been known to come in for a restorative Coke, along with a bag of chips and a cheesesteak.

“You have the salt, the caffeine, and the grease,” she said.

One gentleman, she said, swears by a concoction of Alka Seltzer and one teaspoon each of vinegar and yellow mustard. Science hasn’t quite caught up with that one yet, perhaps.

No account of hangover remedies would be complete without mention of the oft-touted “hair of the dog” approach — i.e., drinking more alcohol.

Swift said more alcohol may indeed reduce symptoms, but only for a time, and he advises against it.

Here’s what happens: In addition to ethanol, alcoholic drinks may contain small amounts of methanol, which the body breaks down into toxic formaldehyde and formic acid.

The same enzymes break down both ethanol and methanol, but they “prefer” to metabolize ethanol, Swift said. Thus, replenishing the supply of ethanol, or so the theory goes, would postpone the breakdown of methanol — making the person feel better for a while.

“It just delays the inevitable, I would think,” he said, adding that moderation is the best approach. “The best way to treat a hangover is not to get one in the first place.”

Whatever the future holds for the field of hangover research, perhaps no study will emerge on a day with a stronger connection to the cause of the malady.

Tom Avril

at 215-854-2430 or tavril@phillynews.com

To see more of The Philadelphia Inquirer, or to subscribe to the newspaper, go to http://www.philly.com/inquirer.

Copyright © 2011, The Philadelphia Inquirer

Sometimes the old methods may work best.

Researchers at Thomas Jefferson University say that they've identified a key agent in the brain chemistry responsible for hangover headaches and that a good remedy is one tried by every tormented soul who's ever groped for a morning-after cup of coffee:

Caffeine.

The stimulant has long been an ingredient in over-the-counter headache medications. But the Jefferson study is the first to link caffeine's effectiveness to its ability to block the activity of a chemical called adenosine.

The researchers, who conducted their study on laboratory rats, also found they could relieve alcohol-induced headaches with an anti-inflammatory drug in the same family as ibuprofen. (And yes, there is a way to tell if a rodent feels like your Uncle Ed after a bender. More on that later.)

While the research left some other scientists unconvinced, it represented a foray into an area of medicine that doesn't get much study. That may be because hangovers elicit little sympathy, said alcoholism researcher Robert Swift, a professor of psychiatry and human behavior at Brown University's Alpert Medical School.

"There are people who feel that one deserves to get a hangover, a negative consequence of drinking that might deter further drinking," he said.

Deserved or not, the affliction has stricken mankind at least since biblical times, as another researcher noted a few years ago in the Annals of Internal Medicine. See Isaiah 5:11, which says, "Woe unto them that rise up early in the morning, that they may follow strong drink."

The new study was overseen by Michael L. Oshinsky, director of preclinical research at the Jefferson Headache Center.

In the journal PLoS One, he and colleagues wrote that they began by giving an "inflammatory soup" to the rats -- administered through a small hole in the skull, multiple times over a three-week period, to make them more sensitive. Such rats have previously been shown to be extra-sensitive to some of the same chemicals that trigger migraines in humans.

The researchers then gave the animals the equivalent of one alcoholic drink, and they proceeded to block various steps in the pathway of metabolizing alcohol, so as to see which by-products led to headache-like symptoms.

They concluded that the problem starts with a chemical called acetate. Excess acetate leads in turn to the formation of adenosine, which accumulates in the brain and appears to be a chief culprit in headaches, the authors wrote.

The presence or absence of "headaches" in the animals was determined by prodding them with nylon filaments around the eye area, the same area that becomes tender in some human migraine suffers. A rat that responded by recoiling or stroking its face was deemed to have "hangover-like hypersensitivity." Rats that got caffeine or the anti-inflammatory drug, on the other hand, showed no such reaction.

In a search of the literature, Oshinsky found another intriguing clue. Dialysis clinics used to administer acetate to kidney patients, and 25 percent of them would report getting headaches.

"That was the real instant for me to say, 'Oh, it's the acetate,' " he said.

Swift, the Brown University professor, said the researchers' use of the rat model was "reasonable" and said the breakdown of acetate may indeed contribute to headaches. But he cautioned that a hangover can include plenty of other symptoms, such as nausea, fatigue, and aversion to bright light.

"I don't think we have a definitive answer about what causes hangover," he said. "Nor do we have a definitive cure."

Another source of hangover malaise, Swift said, may be that alcohol causes the liver to release hormones called inflammatory cytokines -- the same chemicals that play a role in making a flu patient feel lousy.

The caffeine finding did not surprise one local observer of alcohol consumption: Michele Eyre, a bartender at Archie's in Jenkintown.

"That does help," she confirmed, when told of the research at Jefferson.

The morning after a night of excess, Eyre said, bleary-eyed patrons have been known to come in for a restorative Coke, along with a bag of chips and a cheesesteak.

"You have the salt, the caffeine, and the grease," she said.

One gentleman, she said, swears by a concoction of Alka Seltzer and one teaspoon each of vinegar and yellow mustard. Science hasn't quite caught up with that one yet, perhaps.

No account of hangover remedies would be complete without mention of the oft-touted "hair of the dog" approach -- i.e., drinking more alcohol.

Swift said more alcohol may indeed reduce symptoms, but only for a time, and he advises against it.

Here's what happens: In addition to ethanol, alcoholic drinks may contain small amounts of methanol, which the body breaks down into toxic formaldehyde and formic acid.

The same enzymes break down both ethanol and methanol, but they "prefer" to metabolize ethanol, Swift said. Thus, replenishing the supply of ethanol, or so the theory goes, would postpone the breakdown of methanol -- making the person feel better for a while.

"It just delays the inevitable, I would think," he said, adding that moderation is the best approach. "The best way to treat a hangover is not to get one in the first place."

Whatever the future holds for the field of hangover research, perhaps no study will emerge on a day with a stronger connection to the cause of the malady.

Tom Avril

at 215-854-2430 or tavril@phillynews.com

To see more of The Philadelphia Inquirer, or to subscribe to the newspaper, go to http://www.philly.com/inquirer.

Copyright © 2011, The Philadelphia Inquirer

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High School Athlete Handles Celiac Disease

Posted Dec 23, 2010

Dec. 16–Ryan Yates is a typical high school athlete on the outside.

He likes to practice and play hard, and he enjoys spending time with friends.

On the inside, the Dickinson High senior wrestler has gone through quite a battle.

Yates was diagnosed with celiac disease that caused him to miss the 2009 high school football season.

“I was tired and couldn’t do much, really,” Yates said. “I had to lay low.”

Celiac disease is an autoimmune disorder that causes the body to attack the small intestine. Eating certain foods with gluten, a protein found in most bread and cereals, can aggravate the condition. Typical symptoms of celiac disease are abdominal pain, diarrhea and fatigue.

He had to get used to a new diet and the get back into shape for the wrestling season.

It wasn’t an easy road back.

“I was out of shape,” Yates said. “It took hard work. It was tougher than for those who played football.”

But Yates fought through the season and placed fifth at the Class A state wrestling tournament in February in Fargo.

“It felt like all of that hard work paid off,” Yates said.

Yates found out he had celiac disease after having an allergic reaction to some food he ate during a family reunion last year.

After visits to a specialist, Yates diagnoses was confirmed.

Gone are the days of chowing down on hamburgers, hot dogs and sandwiches. Yates doesn’t have to completely abstain from those foods, though.

“I have to watch what I eat,” Yates said. “If I eat more than I’m supposed to, I’ll get sick.”

It complicates eating habits on road trips where the typical meal for the wrestling team is a sandwich.

“But I can eat more meat without any bread. ”

For him, it’s about self control.

“I can’t go hog wild,” Yates said.

With the Dickinson Classic tournament coming up this Friday and Saturday at Dickinson High School, Yates hopes to continue a strong season.

“It will be my last tournament in Dickinson and I want to win it,” Yates said.

He’s 8-2 so far this season and is ranked third in the Class A coaches’ poll in his weight class.

“Last year, he had a good year going into state and had a good finish,” Dickinson head coach Cody Wolf said. “This year, I think he’ll carry it into some of the big tournaments.”

The ultimate goal is to hoist a state championship trophy Feb. 19 at the Fargodome. Yates admits it won’t come easy.

“I want a state title, but I have to keep working hard at it,” Yates said.

Editor’s note: The only treatment for celiac disease is a completely gluten-free diet. Breads that are gluten free may be eaten.

To see more of The Dickinson Press, or to subscribe to the newspaper, go to http://www.thedickinsonpress.com.

Copyright © 2010, The Dickinson Press, N.D.

Dec. 16--Ryan Yates is a typical high school athlete on the outside.

He likes to practice and play hard, and he enjoys spending time with friends.

On the inside, the Dickinson High senior wrestler has gone through quite a battle.

Yates was diagnosed with celiac disease that caused him to miss the 2009 high school football season.

"I was tired and couldn't do much, really," Yates said. "I had to lay low."

Celiac disease is an autoimmune disorder that causes the body to attack the small intestine. Eating certain foods with gluten, a protein found in most bread and cereals, can aggravate the condition. Typical symptoms of celiac disease are abdominal pain, diarrhea and fatigue.

He had to get used to a new diet and the get back into shape for the wrestling season.

It wasn't an easy road back.

"I was out of shape," Yates said. "It took hard work. It was tougher than for those who played football."

But Yates fought through the season and placed fifth at the Class A state wrestling tournament in February in Fargo.

"It felt like all of that hard work paid off," Yates said.

Yates found out he had celiac disease after having an allergic reaction to some food he ate during a family reunion last year.

After visits to a specialist, Yates diagnoses was confirmed.

Gone are the days of chowing down on hamburgers, hot dogs and sandwiches. Yates doesn't have to completely abstain from those foods, though.

"I have to watch what I eat," Yates said. "If I eat more than I'm supposed to, I'll get sick."

It complicates eating habits on road trips where the typical meal for the wrestling team is a sandwich.

"But I can eat more meat without any bread. "

For him, it's about self control.

"I can't go hog wild," Yates said.

With the Dickinson Classic tournament coming up this Friday and Saturday at Dickinson High School, Yates hopes to continue a strong season.

"It will be my last tournament in Dickinson and I want to win it," Yates said.

He's 8-2 so far this season and is ranked third in the Class A coaches' poll in his weight class.

"Last year, he had a good year going into state and had a good finish," Dickinson head coach Cody Wolf said. "This year, I think he'll carry it into some of the big tournaments."

The ultimate goal is to hoist a state championship trophy Feb. 19 at the Fargodome. Yates admits it won't come easy.

"I want a state title, but I have to keep working hard at it," Yates said.

Editor's note: The only treatment for celiac disease is a completely gluten-free diet. Breads that are gluten free may be eaten.

To see more of The Dickinson Press, or to subscribe to the newspaper, go to http://www.thedickinsonpress.com.

Copyright © 2010, The Dickinson Press, N.D.

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Many Kids Are Dehydrated

Posted Dec 18, 2010

Children and teens aren’t staying hydrated enough, a new study reports.

Though kids are likely to drink sugary beverages with their meals, they tend to fall short of the recommended guidelines. Especially in humid Florida weather, children need to replace the water they sweat or face dehydration that can cause fatigue and dizziness, headaches and muscle weakness.

Researchers studied nearly 4,000 children from age 2 to 19 who participated in the National Health and Nutrition Examination Survey in 2005 and 2006.

Children ages 2 to 5 drank about 6 cups of water per day, while children ages 6 to 11 drank 6 and three-quarters cups per day. The 12- to 19-year-olds drank about 10 cups per day.

Girls were less likely to drink an adequate amount of water than boys.

There’s no simple answer to how much water people should drink, according to the Mayo Clinic. It depends on how active you are and where you live. The Institute of Medicine recommends that teenage boys drink about 11 cups per day, while adult men drink 13 cups and women drink 9 cups each day.

Here’s how to get more water into your diet:

–Keep a water bottle by your desk and refill it throughout the day.

–Eat fruits and vegetables because they are natural water sources. Oranges are 87 percent water and cucumbers contain 95 percent.

–You can drink other beverages like coffee, beer, and fruit juices to count toward your fluid intake, but they will add calories to your diet.

–Pair lunch and dinner meals with water to lose weight. Dieters who drank two cups of water before every meal lost an average of 15.5 pounds over one year, compared to 11 pounds among those who did not, according to a study released in August in the journal Obesity.

—–

To see more of The Orlando Sentinel or to subscribe to the newspaper, go to http://www.OrlandoSentinel.com.

Copyright © 2010, The Orlando Sentinel, Fla.

Distributed by McClatchy-Tribune Information Services.

Children and teens aren't staying hydrated enough, a new study reports.

Though kids are likely to drink sugary beverages with their meals, they tend to fall short of the recommended guidelines. Especially in humid Florida weather, children need to replace the water they sweat or face dehydration that can cause fatigue and dizziness, headaches and muscle weakness.

Researchers studied nearly 4,000 children from age 2 to 19 who participated in the National Health and Nutrition Examination Survey in 2005 and 2006.

Children ages 2 to 5 drank about 6 cups of water per day, while children ages 6 to 11 drank 6 and three-quarters cups per day. The 12- to 19-year-olds drank about 10 cups per day.

Girls were less likely to drink an adequate amount of water than boys.

There's no simple answer to how much water people should drink, according to the Mayo Clinic. It depends on how active you are and where you live. The Institute of Medicine recommends that teenage boys drink about 11 cups per day, while adult men drink 13 cups and women drink 9 cups each day.

Here's how to get more water into your diet:

--Keep a water bottle by your desk and refill it throughout the day.

--Eat fruits and vegetables because they are natural water sources. Oranges are 87 percent water and cucumbers contain 95 percent.

--You can drink other beverages like coffee, beer, and fruit juices to count toward your fluid intake, but they will add calories to your diet.

--Pair lunch and dinner meals with water to lose weight. Dieters who drank two cups of water before every meal lost an average of 15.5 pounds over one year, compared to 11 pounds among those who did not, according to a study released in August in the journal Obesity.

-----

To see more of The Orlando Sentinel or to subscribe to the newspaper, go to http://www.OrlandoSentinel.com.

Copyright © 2010, The Orlando Sentinel, Fla.

Distributed by McClatchy-Tribune Information Services.

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Diagnosis Sends Woman on Celiac Crusade

Posted Dec 9, 2010

More than five years ago, West Scranton resident Laure Stasik was diagnosed with celiac disease.

The diagnosis forever changed her life.

“I thought, well I have it, so what do I do with it,” Ms. Stasik, a registered nurse and dietitian, said. “I knew I needed to do something for celiac disease.”

Ms. Stasik, 51, immediately sprang into action.

She opened Alternative Eating, a specialty health food store specifically designed to cater to people who are battling the rare disease and who require gluten-free foods.

She also hit the lecture circuit, donating much of her time talking about the autoimmune illness that affects one in 133 people and requires complete elimination of wheat, barley, rye and oats, and any derivative of those grains.

Celiac disease damages the small intestine and interferes with the absorption of nutrients that’s caused by the consumption of gluten, the protein found in barley, rye and all forms of wheat.

Underdiagnosed

About three million Americans have the disease, while 95 percent of cases are either undiagnosed or misdiagnosed, according to the National Foundation for Celiac Awareness.

“But, when you speak with some people, they believe the number is more like 1 in 55 who have the disease,” Ms. Stasik said. “We’re a growing population. The symptoms are typically gastrointestinal, but mine were numbness, shortness of breath and joint pain. I’m a nurse and a dietitian, so you’d think that I would know.”

Other symptoms include fatigue and there are no medications for it. Staff at the University of Maryland have been working to find appropriate medication and, hopefully, a cure for celiac disease, Ms. Stasik said.

The West Scranton High School and Marywood University graduate recently held a picnic fundraiser at Nay Aug Park where she helped to raise about $8,000 to assist the research going on in Maryland.

She also sells the green celiac awareness bracelets and magnets with all proceeds from those sales going to help research.

The magnets have the Center for Celiac Research’s website address imprinted on them, which allows doctors to easily access information quickly, Ms. Stasik said.

“The picnic is the first of what will be many. It was a great time and there were more than 100 people who came out to support it,” she said. “My message to a person who is diagnosed is for them to take a deep breath and to remember that this can be managed through diet.

The transformation of a diet can be traumatic, she said.

“You have to give up on so much food and then you can’t have that spontaneity of just going out to a restaurant,” Ms. Stasik said. “I had to stop taking Communion because the host is made of wheat.”

So, at Ms. Stasik’s store, her products include a large selection of frozen foods, baked goods, pasta and other food that doesn’t contain gluten.

“It’s hard to tell someone they can’t have Old Forge pizza anymore,” she said.

Ms. Stasik draws inspiration from her mother, Marion, her sister, Ruthie, the late Constance Reynolds and several others, she said.

Crusade for a cure

Not only did her diagnosis act as a catalyst for Ms. Stasik to embark on her crusade of finding a cure for celiac disease, but also to help others who may have the disease, she said.

“Laure has also educated people who suffer from this disease in the local hospitals,” said Noel Adcroft, a friend of Ms. Stasik. “She has truly been a blessing for those who suffer from this disorder.”

Making herself available for fundraisers and talks to encourage others is a must, Ms. Stasik said.

“Saying ‘no’ doesn’t fit into the equation. Whether it’s the professional population or the lay person, if I’m asked to help get the message out, I’m going to do it,” she said.

Meet Laure Stasik

At home: The daughter of Marion Stasik and the late Edward Stasik, Ms. Stasik lives in Scranton with her dog, Cooper.

At work: A registered nurse and dietitian, Ms. Stasik owns and operates Alternative Eating in West Scranton.

Inspirations: Her mother, her sister, Ruthie; the late Constance Reynolds, and others.

Aspiration: To do more for celiac disease awareness.

Diversions: Gardening, talking with friends and colleagues.

Aversions: People who are judgmental and intolerant.

Quote: “People with celiac disease need to know that they are not alone. We’re growing population.”

Contact the writer: sbrown@timesshamrock.com

To see more of The Times-Tribune or to subscribe to the newspaper, go to http://www.thetimes-tribune.com/.

Copyright © 2010, The Times-Tribune, Scranton, Pa.

More than five years ago, West Scranton resident Laure Stasik was diagnosed with celiac disease.

The diagnosis forever changed her life.

"I thought, well I have it, so what do I do with it," Ms. Stasik, a registered nurse and dietitian, said. "I knew I needed to do something for celiac disease."

Ms. Stasik, 51, immediately sprang into action.

She opened Alternative Eating, a specialty health food store specifically designed to cater to people who are battling the rare disease and who require gluten-free foods.

She also hit the lecture circuit, donating much of her time talking about the autoimmune illness that affects one in 133 people and requires complete elimination of wheat, barley, rye and oats, and any derivative of those grains.

Celiac disease damages the small intestine and interferes with the absorption of nutrients that's caused by the consumption of gluten, the protein found in barley, rye and all forms of wheat.

Underdiagnosed

About three million Americans have the disease, while 95 percent of cases are either undiagnosed or misdiagnosed, according to the National Foundation for Celiac Awareness.

"But, when you speak with some people, they believe the number is more like 1 in 55 who have the disease," Ms. Stasik said. "We're a growing population. The symptoms are typically gastrointestinal, but mine were numbness, shortness of breath and joint pain. I'm a nurse and a dietitian, so you'd think that I would know."

Other symptoms include fatigue and there are no medications for it. Staff at the University of Maryland have been working to find appropriate medication and, hopefully, a cure for celiac disease, Ms. Stasik said.

The West Scranton High School and Marywood University graduate recently held a picnic fundraiser at Nay Aug Park where she helped to raise about $8,000 to assist the research going on in Maryland.

She also sells the green celiac awareness bracelets and magnets with all proceeds from those sales going to help research.

The magnets have the Center for Celiac Research's website address imprinted on them, which allows doctors to easily access information quickly, Ms. Stasik said.

"The picnic is the first of what will be many. It was a great time and there were more than 100 people who came out to support it," she said. "My message to a person who is diagnosed is for them to take a deep breath and to remember that this can be managed through diet.

The transformation of a diet can be traumatic, she said.

"You have to give up on so much food and then you can't have that spontaneity of just going out to a restaurant," Ms. Stasik said. "I had to stop taking Communion because the host is made of wheat."

So, at Ms. Stasik's store, her products include a large selection of frozen foods, baked goods, pasta and other food that doesn't contain gluten.

"It's hard to tell someone they can't have Old Forge pizza anymore," she said.

Ms. Stasik draws inspiration from her mother, Marion, her sister, Ruthie, the late Constance Reynolds and several others, she said.

Crusade for a cure

Not only did her diagnosis act as a catalyst for Ms. Stasik to embark on her crusade of finding a cure for celiac disease, but also to help others who may have the disease, she said.

"Laure has also educated people who suffer from this disease in the local hospitals," said Noel Adcroft, a friend of Ms. Stasik. "She has truly been a blessing for those who suffer from this disorder."

Making herself available for fundraisers and talks to encourage others is a must, Ms. Stasik said.

"Saying 'no' doesn't fit into the equation. Whether it's the professional population or the lay person, if I'm asked to help get the message out, I'm going to do it," she said.

Meet Laure Stasik

At home: The daughter of Marion Stasik and the late Edward Stasik, Ms. Stasik lives in Scranton with her dog, Cooper.

At work: A registered nurse and dietitian, Ms. Stasik owns and operates Alternative Eating in West Scranton.

Inspirations: Her mother, her sister, Ruthie; the late Constance Reynolds, and others.

Aspiration: To do more for celiac disease awareness.

Diversions: Gardening, talking with friends and colleagues.

Aversions: People who are judgmental and intolerant.

Quote: "People with celiac disease need to know that they are not alone. We're growing population."

Contact the writer: sbrown@timesshamrock.com

To see more of The Times-Tribune or to subscribe to the newspaper, go to http://www.thetimes-tribune.com/.



Copyright © 2010, The Times-Tribune, Scranton, Pa.

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Drowsy Drivers a Big Problem

Posted Dec 4, 2010

If that driver in the next car isn’t speeding, intoxicated or distracted by texting or talking on the phone, there’s a good chance he or she is barely awake.

A new traffic study issued Monday reports that 41 percent of drivers surveyed said they have fallen asleep or nodded off at the wheel at some point in their lives. Eleven percent, representing thousands of drivers across the nation, said it happened to them in the last year, including cases where individuals were asleep for more than a minute on a multilane highway.

The study by the AAA Foundation for Traffic Safety also noted that drowsy driving has been identified as a contributing factor in 16.5 percent of fatal crashes in the U.S. The new analysis, based on crash data from the National Highway Traffic Safety Administration, reports a significantly higher accident rate involving drowsy drivers than many previous estimates.

“Many of us tend to underestimate the negative effects associated with fatigue and sleep deprivation,” said Kathleen Marvaso, a vice president with AAA.

Teenagers and men are much more likely than other groups to fall asleep while driving, according to the results of the AAA telephone survey of 2,000 U.S. residents who are at least 16 years old. The survey’s release coincides with Drowsy Driving Prevention Week.

Tim Desoky, 26, who recently moved to Chicago to attend medical school, said he got his wake-up call about the dangers of drowsy driving after a high school wrestling team practice. Desoky was exhausted but got behind the wheel anyway.

“I was in the far right lane, the road curved but I continued going straight and ended up all the way to the left,” Desoky said. He nearly hit the center divider but awoke when he ran over the shoulder’s safety bumps.

“Luckily, I woke up in time,” he said.

In cases where a crash occurred, men were 61 percent more likely than women to have been drowsy at the time, the survey said. Drivers ages 16 to 24 were 78 percent more likely than drivers between the ages of 40 and 59 to have been drowsy prior to an accident. More than half the crashes where drowsy driving was a factor resulted in the driver drifting into other lanes or off the road.

The study’s authors acknowledged that estimates vary widely on the prevalence of drowsy driving and its role in causing accidents. But it said the major studies of crashes involving drowsy driving were conducted more than 15 years ago and that the issue does not receive as much attention as other leading causes of crashes.

The responses in the new poll indicate that sleepy drivers often fail to realize just how fatigued they are before getting in their vehicles. Some 70 percent said they felt awake enough to drive and then found themselves struggling to stay conscious.

Alexandra Wales, 32, a regional sales manager from Minneapolis in Chicago on business, said she routinely drives long distances for work.

“I’ll fly and then get into a car, sometimes for several hours, sometimes late at night or unfamiliar with my surroundings,” said Wales, who usually calls friends when she’s feeling fatigued. “There have been many times when I can’t see straight anymore.”

The AAA recommended that drivers get at least six hours of sleep the night before a long trip and to travel at times when the driver is normally awake.

Scheduling a break every two hours or every 100 miles is also advised, the AAA said, along with stopping somewhere overnight rather than trying to drive straight through to the destination.

The study noted that drivers who are very sleepy suffer from reduced reaction time and impaired vision and judgment, similar to the effects of driving while drunk. If a driver drinks coffee or other caffeinated beverages to help stay alert, he or she should do so about 30 minutes before driving to give the caffeine time to enter the bloodstream and take effect, the AAA said.

The best deterrent to falling asleep behind the wheel is to travel with an alert passenger, the report noted. But drivers who are alone can police themselves by paying attention to symptoms of sleepiness, some of which are not as obvious as having trouble keeping your eyes open or frequent yawning.

Other warning signs include daydreaming or having disconnected thoughts; feeling irritable and restless; and missing road signs or driving past an intended exit, the report said.

Stelios Makridis, 40, a graduate student at the Illinois Institute of Technology’s Institute of Design, said he knows his body too well to take a chance at driving while tired.

“There were cases when I was really tired so I just took a cab,” Makridis said. “Why would I make it more complicated when I can just get in a cab? It’s so easy.”

jhilkevitch@tribune.com

sedaniels@tribune.com

—–

To see more of the Chicago Tribune, or to subscribe to the newspaper, go to http://www.chicagotribune.com.

Copyright © 2010, Chicago Tribune

If that driver in the next car isn't speeding, intoxicated or distracted by texting or talking on the phone, there's a good chance he or she is barely awake.

A new traffic study issued Monday reports that 41 percent of drivers surveyed said they have fallen asleep or nodded off at the wheel at some point in their lives. Eleven percent, representing thousands of drivers across the nation, said it happened to them in the last year, including cases where individuals were asleep for more than a minute on a multilane highway.

The study by the AAA Foundation for Traffic Safety also noted that drowsy driving has been identified as a contributing factor in 16.5 percent of fatal crashes in the U.S. The new analysis, based on crash data from the National Highway Traffic Safety Administration, reports a significantly higher accident rate involving drowsy drivers than many previous estimates.

"Many of us tend to underestimate the negative effects associated with fatigue and sleep deprivation," said Kathleen Marvaso, a vice president with AAA.

Teenagers and men are much more likely than other groups to fall asleep while driving, according to the results of the AAA telephone survey of 2,000 U.S. residents who are at least 16 years old. The survey's release coincides with Drowsy Driving Prevention Week.

Tim Desoky, 26, who recently moved to Chicago to attend medical school, said he got his wake-up call about the dangers of drowsy driving after a high school wrestling team practice. Desoky was exhausted but got behind the wheel anyway.

"I was in the far right lane, the road curved but I continued going straight and ended up all the way to the left," Desoky said. He nearly hit the center divider but awoke when he ran over the shoulder's safety bumps.

"Luckily, I woke up in time," he said.

In cases where a crash occurred, men were 61 percent more likely than women to have been drowsy at the time, the survey said. Drivers ages 16 to 24 were 78 percent more likely than drivers between the ages of 40 and 59 to have been drowsy prior to an accident. More than half the crashes where drowsy driving was a factor resulted in the driver drifting into other lanes or off the road.

The study's authors acknowledged that estimates vary widely on the prevalence of drowsy driving and its role in causing accidents. But it said the major studies of crashes involving drowsy driving were conducted more than 15 years ago and that the issue does not receive as much attention as other leading causes of crashes.

The responses in the new poll indicate that sleepy drivers often fail to realize just how fatigued they are before getting in their vehicles. Some 70 percent said they felt awake enough to drive and then found themselves struggling to stay conscious.

Alexandra Wales, 32, a regional sales manager from Minneapolis in Chicago on business, said she routinely drives long distances for work.

"I'll fly and then get into a car, sometimes for several hours, sometimes late at night or unfamiliar with my surroundings," said Wales, who usually calls friends when she's feeling fatigued. "There have been many times when I can't see straight anymore."

The AAA recommended that drivers get at least six hours of sleep the night before a long trip and to travel at times when the driver is normally awake.

Scheduling a break every two hours or every 100 miles is also advised, the AAA said, along with stopping somewhere overnight rather than trying to drive straight through to the destination.

The study noted that drivers who are very sleepy suffer from reduced reaction time and impaired vision and judgment, similar to the effects of driving while drunk. If a driver drinks coffee or other caffeinated beverages to help stay alert, he or she should do so about 30 minutes before driving to give the caffeine time to enter the bloodstream and take effect, the AAA said.

The best deterrent to falling asleep behind the wheel is to travel with an alert passenger, the report noted. But drivers who are alone can police themselves by paying attention to symptoms of sleepiness, some of which are not as obvious as having trouble keeping your eyes open or frequent yawning.

Other warning signs include daydreaming or having disconnected thoughts; feeling irritable and restless; and missing road signs or driving past an intended exit, the report said.

Stelios Makridis, 40, a graduate student at the Illinois Institute of Technology's Institute of Design, said he knows his body too well to take a chance at driving while tired.

"There were cases when I was really tired so I just took a cab," Makridis said. "Why would I make it more complicated when I can just get in a cab? It's so easy."

jhilkevitch@tribune.com

sedaniels@tribune.com

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