How many ways can a single supplement called curcumin-derived from the spice known as turmeric-transform your health? Well, if you’re still skeptical that this humble curry spice could benefit practically every single system in your body, prepare to be surprised.
For starters, just consider curcumin’s powerful effect on cognitive health. This herb’s proven ability to balance inflammatory responses, mop up free radicals and break up unhealthy plaques and proteins has made it a prominent focus of research in the area of both memory and mental function.1-5 Curcumin is also an effective natural mood-balancing agent-with research showing that it can enhance the release of key "feel-good" neurotransmitters like serotonin and dopamine, while curbing stress-related behaviors and stimulating brain cell repair.
But that’s not all: Curcumin is a scientifically supported powerhouse when it comes to lung support, too. Animal studies show that supplementation with this compound inhibits the inflammatory signaling factor NFkappaB-resulting in decreased total numbers of allergy-related cells and substances (including white blood cells, eosinophils and IgE) in the lung fluid of mice with sensitive airways.14 In fact, curcumin is demonstrated to modulate a wide array of immune cells and factors-from T and B cells, macrophages and neutrophils to natural killer cells, interleukins and tumor necrosis factor (TNF)-which enhances its ability to maintain a healthy immune balance in the lungs and other parts of your body.
Strong, flexible joints are another well-known benefit of curcumin supplementation, with animal studies showing dose-related benefits in balancing inflammation, cartilage integrity and bone density. This spice can even provide unparalleled support for several key organs: Research indicates that it can improve creatinine and urea clearance from your kidneys, support healthy liver detoxification and ensure a strong, healthy heart muscle, while maintaining free-flowing, flexible arteries with routine use.
Ultimately, a growing body of studies suggests that a high-quality curcumin supplement may be one of the most effective ways to preserve total-body health-and now, researchers have discovered a way to make your daily dose more powerful than ever. Clinical studies show that a new optimized form of curcumin (called Longvida) can boost blood levels of this natural compound significantly higher than more conventional forms, while also boasting the unique ability to cross the blood-brain barrier-making it the only choice for superior results and lasting, lifelong health.23
Longvida is available now from Vitamin Research Products, both as a standalone supplement and as part of the daily brain-boosting formula DejaVida.
References:
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2. Zhang C, Browne A, Child D, Tanzi RE. Curcumin decreases amyloid-beta peptide levels by attenuating the maturation of amyloid-beta precursor protein. J Biol Chem. 2010 Sep 10;285(37):28472-80.
3. Yanagisawa D, Shirai N, Amatsubo T, et al. Relationship between the tautomeric structures of curcumin derivatives and their Abeta-binding activities in the context of therapies for Alzheimer’s disease. Biomaterials. 2010 May;31(14):4179-85.
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5. Frautschy SA, Cole GM. Why pleiotropic interventions are needed for Alzheimer’s disease. Mol Neurobiol. 2010 Jun;41(2-3):392-409.
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9. Wang R, Xu Y, Wu HL, et al. The antidepressant effects of curcumin in the forced swimming test involve 5-HT1 and 5-HT2 receptors. Eur J Pharmacol. 2008 Jan 6;578(1):43-50.
10. Xu Y, Ku BS, Yao HY, et al. The effects of curcumin on depressive-like behaviors in mice. Eur J Pharma col. 2005 Jul 25;518(1):40-6.
11. Bharal N, Sahaya K, Jain S, et al. Curcumin has anticonvulsant activity on increasing current electroshock seizures in mice. Phytother Res. 2008 Dec;22(12):1660-4.
12. Jyoti A, Sethi P, Sharma D. Curcumin protects against electrobehavioral progression of seizures in the iron-induced experimental model of epileptogenesis. Epilepsy Behav. 2009 Feb;14(2):300-8. Epub 2008 Dec 17.
13. Sumanont Y, Murakami Y, Tohda M, et al. Prevention of kainic acid-induced changes in nitric oxide level and neuronal cell damage in the rat hippoca
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17. Mun SH, Kim HS, Kim JW, et al. Oral administration of curcumin suppresses production of matrix metalloproteinase (MMP)-1 and MMP-3 to ameliorate collagen-induced arthritis: inhibition of the PKCdelta/JNK/c-Jun pathway. J Pharmacol Sci. 2009 Sep;111(1):13-21.
18. Clutterbuck AL, Mobasheri A, Shakibaei M, et al. Interleukin-1beta-induced extracellular matrix degradation and glycosaminoglycan release is inhibited by curcumin in an explant model of cartilage inflammation. Ann N Y Acad Sci. 2009 Aug;1171:428-35.
19. Mathy-Hartert M, Jacquemond-Collet I, Priem F, et al. Curcumin inhibits pro-inflammatory mediators and metalloproteinase-3 production by chondrocytes. Inflamm Res. 2009 Dec;58(12):899-908.
20. Osawa T. Nephroprotective and hepatoprotective effects of curcuminoids. Adv Exp Med Biol. 2007;595:407-23.
21. Wongcharoen W, Phrommintikul A. The protective role of curcumin in cardiovascular diseases. Int J Cardiol. 2009 Apr 3;133(2):145-51.
22. Srivastava G, Mehta JL. Currying the heart: curcumin and cardioprotection. J Cardiovasc Pharmacol Ther. 2009 Mar;14(1):22-7.
23. Frautschy SA et al. Efficacy of curcumin formulations in relation to systemic availability in the brain and different blood compartments in neuroinflammatory and AD models at the 39th Annual Meeting of the Society of Neuroscience, Chicago, October 2009.
