Imagine sustained energy...a flawless memory...perfect vision and hearing...and the physical endurance of someone half your age-all as you reach fifty, sixty, seventy and beyond.
This may sound like an unreachable fantasy. But there's no rule that says your health has to fall apart once you reach middle age-especially not when a carefully chosen combination of the right phytonutrients can provide you with comprehensive protection against all of the most common pitfalls of aging ...and add years of vitality onto your life in the process.
Take turmeric, for example: This is the spice that gives curry its kick-but it's also a clinically proven antioxidant powerhouse. Turmeric-and more specifically its primary constituent curcumin-has been tested with great success against of number of inflammation-related conditions, including psoriasis, chronic pancreatitis, inflammatory bowel and eye diseases plus rheumatoid arthritis.1
Green tea is another powerful life-extending nutrient-rich in a number of health-promoting polyphenols, including the powerful antioxidant epigallocatechin-3-gallate (EGCG). Extensive research shows that, among other benefits, green tea can help to balance blood sugar and insulin levels, fight inflammation, protect against stroke-related brain damage and increase cognitive function plus help to prevent atherosclerosis resulting from elevated LDL cholesterol.2-8
Grape seed extract is a good source of a class of phytochemicals called proanthocyanidins and has emerged as another key anti-aging staple. Studies show that this antioxidant compound can support healthy blood pressure and cholesterol levels, reduce plaque-causing lipid peroxidation, inhibit clot-forming platelet aggregation and reduce inflammation.9-11 Other notable benefits of grape seed supplementation include accelerating wound healing and supporting skin health.12-13
As the most popular staple of the "French paradox"-that is, the phenomenon of low rates of coronary artery disease paired with a diet rich in saturated fat-there seems to be no limit to the health benefits of red wine...especially where your heart is concerned. Not only is it packed with both polyphenols and stilbenes-powerful antioxidants that can raise "good" cholesterol and protect against artery damage--- it's also rich in the anti-aging compound resveratrol. Research shows that resveratrol can mimic the beneficial effects of caloric restriction-including improved heart function and bone density, better motor function, delayed cataracts and longer lifespan-without strict dieting.14-19
Your liver is your body's filter, responsible for pushing out damaging toxins on a daily basis-so keeping this organ in perfect shape is another crucial aspect of longevity. Luckily, numerous clinical trials offer compelling modern-day support for the historical use of milk thistle-and more specifically, its main constituent silymarin-for this very purpose. Research shows that daily silymarin supplementation can improve recovery time dramatically in patients with acute hepatitis, cirrhosis, and other forms of liver disease - while additional studies indicate that it can help to maintain healthy blood sugar and offer critical protection against damaging UV radiation.20-23
Finally, the last few decades have seen the ancient herb Ginkgo biloba emerge as a superstar in the supplement world-most notably for its clinically proven benefits to nerve and cognitive health. Extensive research shows that it can increase blood flow to the brain, reduce memory deficit in Alzheimer's patients and boost vision.24-25
The bottom line: Each of these six botanicals is a vital addition to any longevity-boosting supplement regimen-and that's why Vitamin Research Products has combined them all into a single daily formula called
Extension Phytonutrient.
References:
1. Hsu CH, Cheng AL. Clinical studies with curcumin. Adv Exp Med Biol. 2007;595:471-480.
2. Tsuneki H, Ishizuka M, Terasawa M, Wu JB, Sasaoka T, Kimura I. Effect of green tea on blood glucose levels and serum proteomic patterns in diabetic (db/db) mice and on glucose metabolism in healthy humans. BMC Pharmacol, 2004 Aug 26;4(1):18.
3. Lee H, Bae JH, Lee SR. Protective effect of green tea polyphenol EGCG against neuronal damage and brain edema after unilateral cerebral ischemia in gerbils. J Neurosci Res, 2004 Sep 15;77(6):892-900.
4. Kim HK, Kim M, Kim S, Kim M, Chung JH. Effects of green tea polyphenol on cognitive and acetylcholinesterase activities. Biosci Biotechnol Biochem, 2004 Sep;68(9):1977-9.
5. Hussain T, Gupta S, Adhami VM, Mukhtar H. Green tea constituent epigallocatechin-3-gallate selectively inhibits COX-2 without affecting COX-1 expression in human prostate carcinoma cells. Int J Cancer, 2004 Sep 28 [Epub ahead of print].
6. Pezzato E, Sartor L, Dell'aica I, Dittadi R, Gion M, Belluco C, Lise M, Garbisa S. Prostate carcinoma and green tea: PSA-triggered basement membrane degradation and MMP-2 activation are inhibited by (-)epigallocatechin-3-gallate.Int J Cancer, 2004 Dec 10;112(5):787-92.
7. Zhang M, Lee AH, Binns CW, Xie X. Green tea consumption enhances survival of epithelial ovarian cancer. Int J Cancer, 2004 Nov 10;112(3):465.
8. Ouyang P, Peng WL, Lai WY, Xu AL. [Green tea polyphenols inhibit low-density lipoprotein-induced proliferation of rat vascular smooth muscle cells] [Article in Chinese]. Di Yi Jun Yi Da Xue Xue Bao, 2004 Sep;24(9):975-9.
9. Edirisinghe I, Burton-Freeman B, Tissa Kappagoda C. Mechanism of the endothelium-dependent relaxation evoked by a grape seed extract. Clin Sci (Lond). 2008 Feb;114(4):331-7.
10. Freedman JE, Parker C, Li L, et al. Select flavonoids and whole juice from purple grapes inhibit platelet function and enhance nitric oxide release. Circulation. 2001;103:2792-8.
11. Shafiee M, Carbonneau MA, Urban N, Descomps B, Leger CL. Grape and grape seed extract capacities at protecting LDL against oxidation generated by Cu2+, AAPH or SIN-1 and at decreasing superoxide THP-1 cell production. A comparison to other extracts or compounds. Free Radic Res. 2003 May;37(5):573-84.
12. Katiyar SK. Dietary grape seed proanthocyanidins inhibit photocarcinogenesis through prevention of UV-induced suppression of immune responses via induction of interleukin-12 in mice. Presented at the 233rd national meeting of the American Chemical Society, Chicago, March 25, 2007. Abstract: AGFD 011.
13. Hughes-Formella B, Wunderlich O, Williams R. Anti-inflammatory and skin-hydrating properties of a dietary supplement and topical formulations containing oligomeric proanthocyanidins. Skin Pharmacol Physiol. 2007;20(1):43-9. Epub 2006 Oct 11.
14. Baur JA, Pearson KJ, Price NL, et al. Resveratrol improves health and survival of mice on a high-calorie diet. Nature. 2006 Nov 16;444(7117):337-342.
15. Lagouge M, Argmann C, Gerhart-Hines Z, et al. Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha. Cell. 2006 Dec 15;127(6):1109-1122.
16. Pfluger PT, Herranz D, Velasco-Miguel S, Serrano M, Tschà p MH. Sirt1 protects against high-fat diet-induced metabolic damage. Proc Natl Acad Sci USA. 2008;105(28):9793-9798.
17. Sun C, Zhang F, Ge X, et al. SIRT1 improves insulin sensitivity under insulin-resistant conditions by repressing PTP1B. Cell Metab 2007;6:307-319.
18. Pearson KJ, Baur JA, Lewis KN, et al. Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span. Cell Metab. 2008 Aug;8(2):157-168.
19. Barger JL, Kayo T, Vann JM, et al. A low dose of dietary resveratrol partially mimics caloric restriction and retards aging parameters in mice. PLoS ONE. 2008 Jun 4;3(6):e2264.
20. El-Kamary SS, Shardell MD, Abdel-Hamid M, Ismail S, El-Ateek M, Metwally M, Mikhail N, Hashem M, Mousa A, Aboul-Fotouh A, El-Kassas M, Esmat G, Strickland GT. A randomized controlled trial to assess the safety and efficacy of silymarin on symptoms, signs and biomarkers of acute hepatitis. Phytomedicine. 2009 May;16(5):391-400.
21. Huseini HF, Larijani B, Heshmat R, Fakhrzadeh H, Radjabipour B, Toliat T, Raza M. The efficacy of Silybum marianum (L.) Gaertn. (silymarin) in the treatment of type II diabetes: a randomized, double-blind, placebo-controlled, clinical trial. Phytotherapy Research. Published online ahead of print on October 30, 2006.
22. Meeran SM, Katiyar S, Elmets CA, Katiyar SK. Silymarin inhibits UV radiation-induced immunosuppression through augmentation of interleukin-12 in mice. Mol Cancer Ther. 2006 Jul;5(7):1660-8.
23. Svobodova A, Zdarilova A, Maliskova J, Mikulkova H, Walterova D, Vostalova J. Attenuation of UVA-induced damage to human keratinocytes by silymarin. J Dermatol Sci. 2007 Apr;46(1):21-30. Epub 2007 Feb 7.
24. B. Hofferberth. The Efficacy of EGb 761 (Ginkgo biloba extract) in Patients with Senile Dementia of the Alzheimer Type, A double-Blind, Placebo-Controlled Study on Different Levels of Investigation. Human Psychopharmacol 1994, vol. 9, 215-222.
25. Wu ZM, Yin XX, Ji L, Gao YY, Pan YM, Lu Q, Wang JY. Ginkgo biloba extract prevents against apoptosis induced by high glucose in human lens epithelial cells. Acta Pharmacol Sin. 2008 Sep;29(9):1042-50.
Tags: Anti-aging, Anti-inflammatory, Antioxidant, Arthritis, Atherosclerosis, Body, Cancer, Cataracts, Cholesterol, Circulation, Deficit, Diabetes, Endurance, Energy, Flu, Gain, Healing, Heart, Immune, Liver, Memory, prostate, psoriasis, Relaxation, Rheumatoid arthritis, Skin, Tension, Vision, Wound healing
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