March 2007


Natural Health E-News


 

 

March 2007

 

 

 



Studies reveal new migraine remedies  

A migraine is much more than just a bad headache - it's a recurrent, throbbing headache, usually on one side of the head, often accompanied by "auras" such as nausea and sensitivity to light and sound. The pain of migraines can be excruciating and debilitating, lasting for hours or even days. Sometime in their lives, up to 20% of men and up to 35% of women will suffer migraines.



Low CoQ10 is common among migraine sufferers, and supplementing can help.



While most experts agree that migraines are the result of excessive constriction of blood vessels in the head followed by a rebound dilation period, the exact cause of this pattern is not fully known. Some possibilities include abnormal blood flow control, a platelet disorder, a nerve disorder and low serotonin. Studies also indicate that food sensitivities and/or allergies likely contribute to many cases, as may magnesium deficiency.

Recent studies highlight a few natural remedies with the potential to significantly alleviate migraine headaches.

. Coenzyme Q10: This year, US researchers at the Division of Neurology, Cincinnati Children's
Hospital Medical Center, studied 1,550 young subjects (average age 13.3 years) with frequent headaches. They discovered that coenzyme Q10 deficiency was quite common in among the subjects (74.6%), and that supplementation with coenzyme Q10 among those deficient was found to be effective in reducing the frequency of headaches. In all, 46.3% of the patients experienced a 50% reduction in headache frequency.

. Alpha-lipoic acid: In another study, researchers at the University of Liege, Belgium, conducted a randomized, controlled trial on 44 patients diagnosed with migraine headaches (with or without aura). They found that supplementation with lipoic acid reduced the frequency of migraine attacks, the number of headache days and the severity of headaches over the course of three months, while no changes were found among subjects taking the placebo.

. Butterbur: German researchers recently looked at the role of butterbur root extract on migraine prevention in children and adolescents with severe migraines. Previous trials have demonstrated the success of Butterbur in migraine reduction in adults. A total of 108 children and adolescents (6 to 17 years) who suffered from migraines for at least one year were treated with 50 to 150 mg of the butterbur root extract, depending on age, for four months. The researchers found that 77% of patients reported a reduction in the frequency of migraine attacks of at least 50%. Total attack frequency was reduced by 63%, and 91% of patients felt substantially or at least slightly improved. They conclude that butterbur "shows a potential as an effective and well-tolerated migraine prophylaxis also for children and teenagers."

Sources: Headache, 2007; 47(1): 73-80: Headache, 2007; 47(1): 52-57; Headache. 2005 Mar;45(3):196-203



Vitamins boost fertility factors  

Women who take a daily multivitamin tablet and men who take vitamin C supplements can significantly improve their fertility, new research indicates.




Harvard School of Public Health researchers followed 18,000 women over eight years and found that those who took a multivitamin at least six days a week had a 40% lower risk of ovulation problems leading to infertility.

Ovulation problems are the second leading cause of female infertility after blocked fallopian tubes.

"Multivitamins are packed with a large amount of nutrients so we looked at which were crucial, said Jorge Chavarro, the Harvard research fellow who led the study. "As best as we could tell, it looked as if folic acid was the nutrient that played the biggest role."

Mothers lacking in folic acid during pregnancy have an increased chance of giving birth to children with spina bifida, and all women who are pregnant or trying to conceive are advised to take supplements.

For men, too, supplementation can make a difference. Researchers at
Dubai Specialized Medical Center and Research Labs studied 13 infertile males who received 1,000 mg of vitamin C each twice daily. The men ranged in age from 25 to 35 years.

Sperm counts, movement and structure each improved significantly after two months of vitamin C intake, the researchers found. They concluded that "vitamin C supplementation might improve sperm count, motility and morphology and might have a place as an additional supplement to improve semen quality towards conception."

Sources: The Independent - London, Oct 25, 2006; J Med Food. 2006 Fall;9(3):440-42



Magnesium improves asthma in kids  

Magnesium supplements can help ease asthma symptoms in young people, a Brazilian study suggests.



Studies indicate magnesium's bronchodilating effect can be quite rapid.



Researchers at the State University of Campinas Medical School set out to investigate the long-term effects of magnesium supplementation on children and adolescents with "moderate persistent asthma."

Thirty-seven patients ranging in age from seven to 19 years were randomly divided into two groups, one of which received 300 mg of magnesium per day. The other received a placebo. Both groups also received standard asthma medication as needed.

After two months of observation, the researchers concluded that "oral magnesium supplementation helped to reduce bronchial reactivity...., to diminish allergen-induced skin responses and to provide better symptom control in pediatric patients with moderate persistent asthma treated with [inhalers]."

Lung function was similar in the two groups but patients who received magnesium had "fewer asthma exacerbations and used less salbutamol [inhalers] compared to the placebo group."

Source: Eur J Clin Nutr. 2007 Jan;61(1):54-60. Epub 2006 Jun 21



Chromium shines in diabetes studies  

A new study from
Louisiana State University demonstrates that chromium improves blood sugar control and insulin sensitivity among diabetics. In the 10-month study, those who received 500 mcg of chromium picolinate twice a day experienced significantly improved insulin sensitivity, had less weight gain, less abdominal fat and lower glyco-hemoglobin (an indication of sugar-induced damage to tissues).



Reductions in blood sugar, weight and cholesterol levels leave little doubt that chromium may be a wise choice for diabetics.



University of Vermont researchers report similar findings. In their study involving 37 people with type 2 diabetes, individuals who received 1,000 mcg of chromium picolinate daily for six months, along with diabetes medication, showed improved insulin sensitivity and glucose control compared to a placebo group. Those who received supplements also experienced reduced weight gain and fat accumulation.

A third study, this one from
Israel, points to chromium supplementation as beneficial for older people with type 2 diabetes. Along with standard treatment for the disease, 39 people with diabetes received 200 mcg of chromium picolinate twice daily for three weeks. Meanwhile, 39 others received a placebo. The average age of study participants was 73 and all were undergoing rehabilitation following strokes or hip fractures.

The researchers concluded that among elderly diabetic patients undergoing rehabilitation, "dietary supplementation with chromium is beneficial in moderating glucose intolerance. In addition, chromium intake appears to lower plasma lipid levels."

Sources: Diabetes Care. 2006 Aug;29(8):1826-32; Int J Vitam Nutr Res. 2004 May;74(3):178-82



Cranberry studied in arthritis, cancer  

Cranberries have always been colourful and festive but now it appears they also help fight cancer and arthritis. Scientists are pointing to cranberry juice as a useful tonic for people with rheumatoid arthritis and to the cranberry fruit as having possible anticancer effects.



According to researchers, there's a link between urinary tract infections and arthritis, and getting more cranberry can help.



UK Researchers at Kings College London observe a strong link between rheumatoid arthritis and microbial infection, such as urinary tract infection. People with rheumatoid arthritis, they suggest, could benefit from antibacterial measures including "the use of antibiotics, vegetarian diets and high intake of water and fruit juices such as cranberry juice in addition to currently employed treatments."

Sub-clinical urinary tract infections, these same researchers propose, are what trigger rheumatoid arthritis: a chronic, disabling disease affecting mainly older women.

Across the
Atlantic, meanwhile, a University of Massachusetts review looked at the anticancer properties of cranberries. Researchers reviewed a number of trials and concluded that specific cranberry extracts "can inhibit the growth and proliferation of breast, colon, prostate, lung and other tumours...."

Among other ways in which they may fight disease, cranberries appear to be anti-inflammatory and to play a role in the disintegration of tumour cells.

"In fact...the unique combination of phytochemicals found in cranberry fruit may produce synergistic health benefits."

Sources: Clin Dev Immunol. 2006 Mar;13(1):41-8; Journal of Nutrition 137:186s-93s, 2007



Hot pepper compound is anti-cancer  

UK scientists report that capsaicin, the chemical that burns your mouth when you eat hot peppers, can kill cancer cells with little or no harmful side effects.



Researchers say capsaicin can kill cancer cells with no harm to surrounding tissue.



The researchers believe that capsaicin and other similar compounds attack the mitochondria of cancerous cells, causing them to "switch off" and die (apoptosis, or cell death) without harming surrounding tissue. They say the discovery might explain the low incidence of cancer in countries where people eat a lot of chillies like
Mexico and India.

The researchers note the discovery is exciting for two reasons. First, since capsaicin and related compounds already exist in food that is eaten regularly, they are already safe and readily available. Second, these compounds have already been approved for use in a range of drugs such as skin ointments to treat psoriasis and neuralgia. Converting their use to treat cancer would be much cheaper and quicker compared to starting from scratch with a new compound.

Source: Medical News Today, Jan 10, 2007

 

 

 

The obesity answer?

A researcher at the University of Calgary believes she may have found an important weapon in the war against obesity. Dr. Raylene Reimer and her colleagues are launching the first human trials to assess a promising natural fibre, already shown to be effective in tests involving genetically obese rats. "It may not be the magic bullet," Reimer says, "but this will likely be one factor that people can change in their life to help achieve a healthy body weight." The fibre is called oligo fructose, also known as fructo-oligosaccharide, or FOS. In a study with genetically obese rats, Reimer found that FOS helped rats significantly reduce their food intake and improve blood lipid profile. FOS is already included in many probiotic supplements.
Source: University of Calgary, Jan 31, 2007

 

What's hot: Green Tea Extract
What is it?
From green tea leaves (Camellia sinensis), rich in flavonoids and antioxidants.
Why take it?
Reported to fight cancer, HIV, high cholesterol, obesity, dental cavities.
What's the latest research? A study published in 2000 concluded that green tea exerts a thermogenic (fat burning) effect beyond its caffeine content and that it could be useful against obesity. An October 2003 study found that a component in green tea (EGCG) has potent anticancer properties in human prostate cancer cells.

 

Arnica beats NSAID for pain

Over 200 patients with multiple osteoarthritis in the fingers, along with their doctors, found Arnica gel more effective for pain relief than 5% Ibuprofen gel, a non-steroidal anti-inflammatory drug (NSAID). For the study, the patients applied one or the other gel products three times daily to affected finger joints. This is the first study looking at this condition to be performed according to new strict guidelines.
Source: Rheumatol Int DOI 10.1007/s00296-007-0304-y

 

Mineral slows down HIV

Supplements of the mineral selenium appear to reduce or slow the progression of HIV, University of Miami researchers report.Deficiencies in selenium have been noted in HIV-positive patients, and evidence suggests that supplements can improve immune system function."Those individuals who were treated with selenium displayed no further progression of HIV disease, whereas those who were on placebo evidenced a continued increase in HIV viral load," said lead researcher Barry E. Hurwitz. Improvements linked to selenium were seen whether patients were taking HIV antiretroviral drugs or not, Hurwitz said.
Source: Health Day News, Jan 22, 2007

 

Olive oil and ulcers

Compounds in olive oil called polyphenols may prevent infection with the ulcer-causing bacteria Helicobacter pylori, say Spanish researchers. Under their simulated in vitro conditions, extra virgin olive oil had strong antibacterial effects against eight strains of H. pylori, three of which were resistant to antibiotics. "These results open the possibility of considering extra virgin olive oil a chemoprotective agent for peptic ulcer or gastric cancer, but this bioactivity must be confirmed in vivo in the future," wrote the lead author. Previous studies have shown that green tea and cranberry juice also inhibit the growth of H. pylori.
Source: Journal of Agricultural and Food Chemistry, Vol 55, 680-686

 

Melatonin for anti-aging?

A small study suggests that melatonin may protect against age-related diseases. People taking 5 mg daily for one month significantly increased antioxidant defense in red blood cells and decreased indicators of cell aging. The researchers say melatonin may "prevent age-related diseases and prolong the lifespan and improve the quality of life of elderly people."
Source: J Pineal Res, 2007;42(2):153-8.

 

B-vitamin pair protects brain

Folate (folic acid) and vitamin B12 may work together to protect cognitive function among seniors, according to a new study from Tufts University's Jean Mayer USDA Human Nutrition Research Center on Aging. Martha Savaria Morris, PhD, reports "we found a strong relationship between high folate status and good cognitive function among people 60 and older who also had adequate levels of vitamin B12." The study also determined that low vitamin B12 status was associated with increased cognitive impairment. Seniors with low B12 status and high serum folate were also significantly more likely to have anemia. B12 deficiency, which affects many seniors, can impact the production of DNA needed for new cells, as well as neurological function.
Source: Tuft's University, Feb 9, 2007

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